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. 2021 Nov 15;37:100527. doi: 10.1016/j.epidem.2021.100527

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© 2021 The Authors

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 3 — Impacts of NPIs on COVID-19 control., A. Mean reduction in R_E * and B. cumulative cases saved across 50-day simulated epidemics under assumptions of differing non-pharmacological interventions (NPIs). NPIs are color-coded by threshold number of persons for group-size limits, lag-time for symptom-based isolations, and mean turnaround time from test positivity to isolation of infectious individuals for testing isolations. For testing isolations, shading hue corresponds to test limit of detection with the darkest colors indicating the most sensitive tests with a limit of detection of 10¹ virus copies/μl of RNA. Progressively lighter shading corresponds to limits of detection = 10³, 10⁵, and 10⁷ cp/μl. *Note: R_Ereduction (panel A) is calculated as the difference in mean R_Ein the absence vs. presence of a given NPI. The upper confidence limit (uci) in R_Ereduction is calculated as the difference in uci R_Ein the absence vs. presence of NPI. In our model, mean R_Ein the absence of NPI equals 1.05 and uci R_Ein the absence of NPI equals 8.6.