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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Cell Calcium. 2021 Sep 10;99:102472. doi: 10.1016/j.ceca.2021.102472

Fig. 5. Molecular expression of Ca2+ influx channels in ICC.

Fig. 5.

A Relative expression of cellular-specific biomarker genes in ICC (sorted to purity by FACS) and compared with unsorted cells dispersed from gastric antrum and corpus tissues obtained from Kit+/copGFP mice. Relative expression was determined by qPCR and normalized to Gapdh expression. Kit (tyrosine kinase receptor, found in ICC), Ano1 (Ca2+-activated Cl− channel), Myh11 (smooth muscle myosin). PDGFRa (platelet-derived growth factor receptor α cell marker) and Uch11 (neural marker encoding PGP 9.5) B Relative expression of major voltage dependent Ca2+ entry channels, l-Type Ca2+ channels (Cacna1c and Cacna1d) and T-type Ca2+ channels (Cacna1g, Cacna1h and Cacna1i). C Relative expression of the Na+/Ca2+ exchanger (NCX) isoforms (Slc8a1, Slc8a2 and Slc8a3) in gastric antrum and corpus ICC. All data graphed as mean ± SEM (n = 4).