Skip to main content
. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Cell Calcium. 2021 Sep 10;99:102472. doi: 10.1016/j.ceca.2021.102472

Table 1.

Molecular expression quantification of important Ca2+ signaling genes in gastric ICC.

Antrum Unsorted cells ICC P Corpus Unsorted cells ICC P
Kit 0.024 ± 0.0001 0.849 ± 0.0057 **** 0.069 ± 0.0019 0.979 ± 0.0097 ****
Ano1 0.064 ± 0.0008 1.506 ± 0.0286 **** 0.212 ± 0.0012 1.806 ± 0.0408 ****
Myh11 0.640 ± 0.0079 0.280 ± 0.0058 – 1.527 ± 0.0176 0.275 ± 0.0054 –
PDGFRa 0.080 ± 0.0016 0.011 ± 0.0002 – 0.125 ± 0.0012 0.014 ± 0.0021 –
Uchl1 0.024±0.0004 0.017±0.0008 – 0.072±0.0012 0.011±0.0008 –
Cacna1c 0.005 ± 0.0003 0.008 ± 0.0003 **** 0.007 ± 0.0006 0.010 ± 0.0006 –
Cacna1d 0.014 ± 0.0004 0.047 ± 0.0004 **** 0.019 ± 0.0001 0.065 ± 0.0012 ****
Cacna1g 0.001 ± 0.0001 0.004 ± 0.0001 **** 0.004 ± 0.0001 0.005 ± 0.0003 ****
Cacna1h 0.004 ± 0.0005 0.042 ± 0.001 **** 0.004 ± 0.0006 0.061 ± 0.0012 ****
Cacna1i undetected undetected undetected undetected
Slc8a1 0.001 ± 0.00003 0.018 ± 0.0001 **** 0.005 ± 0.0003 0.021 ± 0.0009 ****
Slc8a2 0.001 ± 0.00004 0.017 ± 0.0005 **** 0.005 ± 0.0004 0.016 ± 0.0002 ****
Slc8a3 0.005 ± 0.0001 0.005 ± 0.0001 – 0.006 ± 0.0004 0.005 ± 0.0002 –
Atp2a1 undetected undetected undetected undetected –
Atp2a2 0.139 ± 0.0021 1.469 ± 0.0128 **** 0.372 ± 0.0040 1.584 ± 0.0099 ****
Atp2a3 0.031 ± 0.0006 0.622 ± 0.0062 **** 0.094 ± 0.0003 0.676 ± 0.0067 ****
Itpr1 0.029 ± 0.0002 0.079 ± 0.0010 **** 0.076 ± 0.0033 0.116 ± 0.0005 –
Itpr2 0.012 ± 0.0004 0.007 ± 0.0005 – 0.014 ± 0.0003 0.013 ± 0.0002 NS
Itpr3 0.010 ± 0.00002 0.002 ± 0.00007 – 0.017 ± 0.0009 0.001 ± 0.0001 –
Ryr1 0.0004 ± 0.0001 0.001 ± 0.0001 **** 0.0002 ± 0.0001 0.0004 ± 0.0001 *
Ryr2 0.005 ± 0.001 0.012 ± 0.0006 **** 0.006 ± 0.0002 0.013 ± 0.0011 ****
Ryr3 0.008 ± 0.0002 0.001 ± 0.0005 – 0.019 ± 0.0012 0.001 ± 0.0001 –
Orai1 0.028 ± 0.0003 0.060 ± 0.0043 **** 0.052 ± 0.0006 0.069 ± 0.0025 ****
Orai2 0.010 ± 0.0001 0.003 ± 0.0001 – 0.015 ± 0.0002 0.005 ± 0.0001 –
Orai3 0.013 ± 0.0003 0.042 ± 0.0010 **** 0.038 ± 0.0001 0.047 ± 0.0014 ****
Stim1 0.061 ± 0.0009 0.104 ± 0.0020 **** 0.089 ± 0.0030 0.119 ± 0.0029 ****
Stim2 0.032 ± 0.0012 0.155 ± 0.0055 **** 0.058 ± 0.0009 0.176 ± 0.0041 ****

ANOVA post-test used to derive P values. P values indicated as not significant NS, P < 0.1 *, P < 0.01 **, P < 0.001 *** and P < 0.0001 ****. – indicate no significant gene enrichment in ICC compared to unsorted cell sample. n = 4.