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. 2021 Oct 21;12:754469. doi: 10.3389/fimmu.2021.754469

Table 3.

Prevalence of aPS/PT IgG and IgM antibodies compared to LA, aCL, and aβ2GPI at first sample.

APS/SLE/others patients (n = 79)
LA aCL Ab IgG aβ2GPI Ab IgG LA-aCL-aβ2GPI Ab IgG aCL-aβ2GPI Ab IgG
Positive Negative Positive Negative Positive Negative Triple positive Triple negative Double positive Double negative
n = 25 n = 54 n = 22 n = 57 n = 30 n = 49 n = 16 n = 44 n = 5 n = 44
aPS/PT Ab IgG Kappa: 0.84 Kappa: 0.36 Kappa: 0.22 Kappa: 0.38 Kappa: 0.11 (0 ∈ 95%IC)
Positive 25 (100) 6 (11) 9 (41) 5 (9) 9 (30) 5 (10) 7 (44) 4 (9) 1 (20) 4 (9)
Negative 0 (0) 48 (89) 13 (59) 52 (91) 21 (70) 44 (90) 9 (56) 40 (91) 4 (80) 40 (91)
LA aCL Ab IgM aβ2GPI Ab IgM LA-aCL-aβ2GPI Ab IgM aCL-aβ2GPI Ab IgM
Positive Negative Positive Negative Positive Negative Triple positive Triple negative Double positive Double negative
n = 25 n = 54 n = 20 n = 59 n = 16 n = 63 n = 7 n = 42 n = 5 n = 42
aPS/PT Ab IgM Kappa: 0.35 Kappa: 0.33 Kappa: 0.23 Kappa: 0.42 Kappa: 0.26
Positive 20 (80) 21 (39) 17 (85) 24 (41) 13 (81) 28 (44) 7 (100) 12 (29) 4 (80) 12 (29)
Negative 5 (20) 33 (61) 3 (15) 35 (59) 3 (19) 35 (56) 0 (0) 30 (71) 1 (20) 30 (71)

Values of categorical variables are expressed as number and (percentage). Cohen’s kappa interpretation: poor <0.20; weak 0.21–0.40; moderate 0.41–0.60; good 0.61–0.80; very good 0.81–1.00.

APS, anti-phospholipid syndrome; SLE, systemic lupus erythematous; aPS/PT, anti-phosphatidylserine/prothrombin antibodies.