Table 3.
Prevalence of aPS/PT IgG and IgM antibodies compared to LA, aCL, and aβ2GPI at first sample.
| APS/SLE/others patients (n = 79) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| LA | aCL Ab IgG | aβ2GPI Ab IgG | LA-aCL-aβ2GPI Ab IgG | aCL-aβ2GPI Ab IgG | ||||||
| Positive | Negative | Positive | Negative | Positive | Negative | Triple positive | Triple negative | Double positive | Double negative | |
| n = 25 | n = 54 | n = 22 | n = 57 | n = 30 | n = 49 | n = 16 | n = 44 | n = 5 | n = 44 | |
| aPS/PT Ab IgG | Kappa: 0.84 | Kappa: 0.36 | Kappa: 0.22 | Kappa: 0.38 | Kappa: 0.11 (0 ∈ 95%IC) | |||||
| Positive | 25 (100) | 6 (11) | 9 (41) | 5 (9) | 9 (30) | 5 (10) | 7 (44) | 4 (9) | 1 (20) | 4 (9) |
| Negative | 0 (0) | 48 (89) | 13 (59) | 52 (91) | 21 (70) | 44 (90) | 9 (56) | 40 (91) | 4 (80) | 40 (91) |
| LA | aCL Ab IgM | aβ2GPI Ab IgM | LA-aCL-aβ2GPI Ab IgM | aCL-aβ2GPI Ab IgM | ||||||
| Positive | Negative | Positive | Negative | Positive | Negative | Triple positive | Triple negative | Double positive | Double negative | |
| n = 25 | n = 54 | n = 20 | n = 59 | n = 16 | n = 63 | n = 7 | n = 42 | n = 5 | n = 42 | |
| aPS/PT Ab IgM | Kappa: 0.35 | Kappa: 0.33 | Kappa: 0.23 | Kappa: 0.42 | Kappa: 0.26 | |||||
| Positive | 20 (80) | 21 (39) | 17 (85) | 24 (41) | 13 (81) | 28 (44) | 7 (100) | 12 (29) | 4 (80) | 12 (29) |
| Negative | 5 (20) | 33 (61) | 3 (15) | 35 (59) | 3 (19) | 35 (56) | 0 (0) | 30 (71) | 1 (20) | 30 (71) |
Values of categorical variables are expressed as number and (percentage). Cohen’s kappa interpretation: poor <0.20; weak 0.21–0.40; moderate 0.41–0.60; good 0.61–0.80; very good 0.81–1.00.
APS, anti-phospholipid syndrome; SLE, systemic lupus erythematous; aPS/PT, anti-phosphatidylserine/prothrombin antibodies.