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. 2021 Nov 1;14:739526. doi: 10.3389/fnmol.2021.739526

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Copyright © 2021 Yin, Ma, Luo, Luo, He, Liang, Zuo, Xu, Chen, Xiong, Tan, Fu, Lv, Dai, Wen, Zhu, Ye, Lin, Lin, Li, Chen, Luo, Li and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Discrimination of glyoxalase 1 (Glo-1) mRNA levels (A) and enzymatic activity levels (B) in peripheral blood from the first-onset antipsychotic-naïve patients with schizophrenia and healthy controls. A receiver operating characteristic (ROC) curve was constructed to evaluate the role of Glo-1 mRNA expression (C) and enzymatic activity (D) in the diagnosis of schizophrenia. Discrimination of Glo-1 mRNA levels (E) and enzymatic activity levels (F) in genotypes of rs1781735 in peripheral blood of first-onset antipsychotic-naïve patients with schizophrenia and healthy controls. AUC, the area under the ROC curve. *, P < 0.05. ***, P < 0.001. The error bar represents the SD of the mean.