Hu 2018.

Study characteristics
Methods	Aim: to explore the effect of escitalopram on the neural function and cognitive function of patients with post‐stroke depression RCT
Participants	82 stroke patients selected who were in hospital from October 2016 to October 2017. Met diagnostic criteria for stroke. Both haemorrhagic and ischaemic stroke included. Patients also met the diagnostic criteria of depression in Chinese classification of mental disorders; Patients did not take other antidepressants before; HAMD Score > 18 Exclusions: 1) patients with transient cerebral ischaemia, secondary cerebral ischaemia and cerebral infarction; 2) patients with haematological diseases, coagulation dysfunction, arteriovenous malformations; 3) patients with severe organ diseases, respiratory failure; 4) patients taking other antidepressants recently; 5) patients with severe depression and cognitive impairment; 6) patients allergic to the study drugs, and dropped out of the study
Interventions	Both groups were given usual medical care, the treatment group was given escitalopram oxalate tablets (H20103327, Shandong Jingwei Pharmaceutical Co., Ltd. 10mg*7 tablets) 10mg, once per day, for 12 weeks
Outcomes	HAMD score NIHSS score MMSE score FIM score
Funding source	Scientific research program of Shandong Provincial Department of Health (Funding number: 2012ws1783)
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Random number table method
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Not described
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not described
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Not described
Selective reporting (reporting bias)	Unclear risk	No protocol available to check
Other bias	Unclear risk	Not described