Liu 2006.

Study characteristics
Methods	Parallel design Aim: to study effect of citalopram on post‐stroke depression and neurological functional rehabilitation
Participants	Country: China Setting: inpatient Stroke criteria: stroke during "recovery phase" at 6 to 9 months, NIHSS score ≥ 13, HAMD score ≥ 17 60 people randomised, of whom 38 were men, mean age 60.7 ± 8.6 years. Demographics for treatment and control groups were not provided Treatment: 30 people, age and gender not stated Control: 30 people, age and gender not stated Exclusion criteria: previous psychiatric disorder, dementia, aphasia, consciousness disturbance
Interventions	Treatment: citalopram 20 mg daily plus routine stroke care Control: routine stroke care Duration of treatment: 6 weeks Duration of follow‐up (treatment end to study end): 0
Outcomes	HAMD NIHSS BI Death
Funding source	Source of funding not stated
Notes	AEs not reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Method not described
Allocation concealment (selection bias)	Unclear risk	Not described
Blinding of participants and personnel (performance bias) All outcomes	High risk	No placebo
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not stated
Incomplete outcome data (attrition bias) All outcomes	Low risk	No dropouts
Selective reporting (reporting bias)	Unclear risk	No protocol
Other bias	Unclear risk	Baseline balance reported by authors