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. 2021 Nov 15;2021(11):CD009286. doi: 10.1002/14651858.CD009286.pub4

NCT02737930.

Study characteristics
Methods RCT
Participants Acute stroke
18 Years to 85 years
MRI‐confirmed acute ischaemic stroke resulting in an isolated homonymous visual field loss
17 enrolled up to August 2020. No results published
Interventions Fluoxetine 20mg for 90 days or matching placebo
Outcomes Improvement in size of visual field deficit (degrees) (primary outcome)
Secondary outcomes: improvement in size of visual field deficit (square degrees), Improvement in parametric mean deviation
Functional field score
Visual Function Questionnaire‐25 score
Patient Health Questionnaire‐9 score
mRS score
Post‐stroke changes in cortical visual representation as measured by functional MRI
Post‐stroke changes in retinal nerve fibre layer thickness
Funding source Bogachan Sahin
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk No published data
Allocation concealment (selection bias) Unclear risk No published data