Study	Reason for exclusion
ACTRN12619000573156	Trial abandoned prior to initiating recruitment due to COVID‐19 pandemic
Andersen 1993	Cross‐over design: double‐blind placebo‐controlled cross‐over protocol as follows: 7 days initial baseline registration, 21 days citalopram or placebo (randomised), 7 days wash‐out, 7 days baseline registration, and cross‐over to second 21‐day treatment period
Andersen 2012	The trial never started
Anderson 2002	The trial never started
Anonymous 2012a	Unable to find publication after extensive searching
Anonymous 2012b	Unable to find publication after extensive searching
Berends 2009	Mean time from stroke onset to fluoxetine was 39.1 months
Bonin Pinto 2019	Participants were recruited within 2 years (not 1 year) of stroke
Chen 2019	Tandospirone + escitalopram (combination therapy) and escitalopram (monotherapy) in people with vascular depression
Choi Kwon 2008	Participants more than 1 year post‐stroke
Finkenzeller 2009	SSRI plus active intervention (psychotherapy) versus active treatment (psychotherapy) alone. This trial had been included in the original 2012 review but due to the potential interaction between the SSRI and psychotherapy we decided to exclude it in this update
Foster 2019	2 arms: 1 with SSRI plus exercise and 1 arm with placebo plus exercise
Gourab 2015	Time of stroke onset > 12 months
Graffagnino 2002	Previously listed in 'Studies awaiting classification' (Mead 2012). Unable to access any full publication and we received no response from the author. Given the insufficient information to assess eligibility and, owing to the length of time since the study abstract (2002) was published, we have now excluded this study. CRSREF: 3340767
Ji 2000	SSRI plus active intervention versus active treatment alone
Kitago 2020	Combined intervention
Li 2002	There is no random component in the sequence generation process
Liang 2003	There is no random component in the sequence generation process. This had been included in the 2012 review but on review of the methodology the review authors decided to exclude this for the update
Liu 2004	SSRI plus active intervention versus active treatment alone
Liu 2020	Wrong comparator
Mosarrezaii 2018	Qu0te: "Patients received numbered cards according to the order of hospitalization. The recipients of the cards with odd and even numbers constituted the case and control group, respectively." Allocation concealment procedure was inadequately concealed
NCT01963832	Study withdrawn (not funded)
Robinson 2011	Ineligible outcomes: prevention of generalised anxiety disorder
Sitzer 2002	Previously listed in 'Studies awaiting classification' (Mead 2012). Unable to access any full publication and we received no response from the author. Given the insufficient information to assess eligibility and, owing to the length of time since the study abstract (2002) was published, we have now excluded this study
Sun 2015	Mean time since onset 19.2 ± 3.5 months. No placebo or usual‐care control group (Prozac, acupuncture, and prozac plus acupuncture)
Vogel 2020	Open‐label single‐group study
Xu 2007	This had been included in the 2012 review but it compares fluoxetine plus wulung capsule versus wulung capsule alone. Wulung capsule is an active comparator so we have therefore excluded this trial for this update
Zhou 2003	There is no random component in the sequence generation process. This trial had been included in the 2012 version of the review but for this update we excluded it

SSRI: selective serotonin reuptake inhibitor