Table 2.
Laboratory findings of acute chikungunya in children and adults (N = 50)
| Laboratory profile | Children (N = 10) | Adults (N = 40) | P value | Adjusted P value | ||
|---|---|---|---|---|---|---|
| n | Median (IQR) | n | Median (IQR) | |||
| Ct value | 10 | 19.63 (18.01–24.64) | 40 | 23.55 (17.93–30.68) | 0.159 | 1.000 |
| Leukocytes/µL | 10 | 7,590 (4,300–9,042) | 39 | 6,200 (4,365–7,470) | 0.184 | 1.000 |
| Neutrophils/µL | 10 | 4,093 (2,631–6,837) | 39 | 3,230 (2,582–4,210) | 0.472 | 1.000 |
| Lymphocytes/µL | 10 | 1,093 (661–3,065) | 39 | 948 (572–1,690) | 0.286 | 1.000 |
| Monocytes/µL | 10 | 747 (281–966) | 39 | 507 (391–629) | 0.372 | 1.000 |
| Eosinophils/µL | 10 | 15 (7–132) | 39 | 21 (5–84) | 0.980 | 1.000 |
| Basophils/µL | 10 | 32 (6–94) | 39 | 12 (0–36) | 0.125 | 1.000 |
| Hemoglobin g/dL | 10 | 12.65 (11.15–13.85) | 40 | 12.81 (11.30–13.85) | 0.689 | 1.000 |
| Hematocrit (%) | 10 | 37.90 (34.65–43.60) | 40 | 38.40 (33.63–41.48) | 0.743 | 1.000 |
| Platelets (103/µL) | 10 | 191 (165–296) | 40 | 166 (139–196) | 0.087 | 1.000 |
| Total bilirubin (mg/dL) | 8 | 0.9 (0.4–3.3) | 29 | 0.5 (0.3–4.1) | 0.372 | 1.000 |
| Direct bilirubin (mg/dL) | 8 | 0.4 (0.2–32) | 29 | 0.2 (0.2–0.3) | 0.454 | 1.000 |
| Total protein (g/dL) | 8 | 7.5 (7.0–13.4) | 28 | 7 (6.1–7.7) | 0.127 | 1.000 |
| Albumin (g/dL) | 8 | 4.5 (4.2–9.15) | 27 | 4.1 (3.9–4.4) | 0.011 | 0.286 |
| Globulin (g/dL) | 8 | 2.25 (0.8–2.9) | 25 | 3 (2.4–3.4) | 0.033 | 0.858 |
| Albumin/globulin ratio | 8 | 1.61 (1.45–2.02) | 27 | 1.34 (1.22–1.58) | 0.054 | 1.000 |
| ALP (IU/L) | 9 | 165 (1.5–286) | 29 | 65 (57–88) | 0.110 | 1.000 |
| AST (IU/L) | 9 | 47 (20–88) | 32 | 38 (29–47) | 0.765 | 1.000 |
| ALT (IU/L) | 9 | 35 (23–44) | 32 | 38 (23–49) | 0.682 | 1.000 |
| GGT (IU/L) | 7 | 46 (16-167) | 25 | 50 (33–77) | 0.802 | 1.000 |
| BUN (mg/dL) | 5 | 11 (9.5–14) | 24 | 15 (10.2–18.7) | 0.184 | 1.000 |
| Creatinine (mg/dL) | 5 | 0.57 (0.51–0.70) | 30 | 1.08 (0.77–1.35) | 0.002 | 0.052 |
| CRP (mg/dL) | 7 | 3.26 (0.95–4.61) | 33 | 2.88 (1.5–5.02) | 0.957 | 1.000 |
| LDH | 0 | 0 | 4 | 375 (368–388) | NA | NA |
| Creatinine kinase | 1 | 1,706 (1,706–1,706) | 6 | 381 (88–1,108) | 0.317 | 1.000 |
| INR | 0 | 0 | 3 | 14.92 (1.15) | NA | NA |
ALP = alkaline phosphatase; ALT = alanine transaminase; AST = aspartate aminotransferase; BUN = blood urea nitrogen; CRP = C-reactive protein; Ct = cycle threshold; GGT = gamma-glutamyl transpeptidase; INR = international normalized ratio; LDH = lactate dehydrogenase. Bold values are the P values which were found statistically significant.