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. 2021 Sep 7;105(5):1326–1334. doi: 10.4269/ajtmh.20-1063

Table 3.

Factors associated with unsuccessful tuberculosis treatment outcome. Antioquia, Colombia, 2014 to 2016

Variables Successful treatment,
N = 4,523,
n (%)
Unsuccessful treatment,
N = 1,633,
n (%)
RR (95% CI) Adjusted RR (95% CI)
Age in years
 < 15 900 (80.8) 214 (19.2) 1 1
 1554 2,930 (73.2) 1,073 (26.8) 1.4 (1.2–1.6) 1.2 (1–1.3)
 ≥ 55 520 (70.8) 214 (29.2) 1.5 (1.3–1.8) 1.7 (1.4–2)
Male sex 2,673 (69.4) 1,181 (30.6) 1.6 (1.4–1.7) 1.3 (1.2–1.4)
Ethnicity
 Indigenous 47 (78.3) 13 (21.7) 1
 Afro-Colombian 102 (77.9) 29 (22.1) 1 (0.6–1.8)
 Other 4,374 (73.3) 1,591 (26.7) 1.2 (0.8–2)
Living area
 Urban 3,379 (72.7) 1,271 (27.3) 1 1
 Rural 192 (79) 51 (21) 0.8 (0.6–1) 0.8 (0.6–1.1)
 Scattered rural 170 (78.7) 46 (21.3) 0.8 (0.6–1) 0.7 (0.5–0.9)
Health insurance
 Contributive 2,411 (87.2) 354 (12.8) 1 1
 Subsidized 1,877 (64.1) 1,049 (35.9) 2.8 (2.5–3.1) 2.4 (2.1–2.8)
 Poor without health insurance 235 (50.5) 230 (49.5) 3.9 (3.4–4.4) 2.5 (2.1–3)
 Healthcare worker 83 (90.2) 9 (9.8) 0.4 (0.2–0.7)
 Homeless individuals 196 (35.8) 352 (64.2) 2.8 (2.6–3) 1.5 (1.3–1.7)
 Prisoners 68 (81.9) 15 (18.1) 0.7 (0.4–1.1)
Disease form
 Pulmonary 3,657 (72) 1,423 (28) 1 1
 Extrapulmonary 866 (80.5) 210 (19.5) 0.5 (0.4–0.6) 0.8 (0.7–1)
HIV 486 (58.6) 344 (41.4) 1.8 (1.7–2) 1.5 (1.4–1.7)
Diabetes 101 (83.5) 20 (16.5) 0.6 (0.4–0.9)
Chronic obstructive pulmonary disease 35 (81.4) 8 (18.6) 0.7 (0.4–1.3)
Drug disorder 122 (55.2) 99 (44.8) 1.7 (1.9–2)
Chronic kidney disease 23 (67.6) 11 (32.4) 1.2 (0.7–2)
Other immunodeficiency disorders 30 (73.2) 11 (26.8) 1 (0.3–1.7)
Previously treated patient 384 (45.8) 454 (54.2) 2.5 (2.3–2.7) 1.7 (1.5–1.9)
Hospital diagnosis 1,771 (67) 872 (33) 1.6 (1.5–1.8) 1.4 (1.3–1.6)
Year of notification
 2014 1,765 (74.9) 591 (25.1) 1 1
 2015 1,345 (72.8) 502 (27.2) 1.1 (0.9–1.2) 1.01 (0.89–1.14)
 2016 1,413 (72.4) 540 (27.6) 1.1 (0.9–1.2) 1.06 (0.94–1.2)

RR = relative risk.