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. 2021 Nov 15;16(11):e0259663. doi: 10.1371/journal.pone.0259663

Table 2. Odds ratios of APOE4 for developing MCI and dementia, stratified by genotype of VC transporter genes.

Gene symbol SNP ID Genotype group APOE4
Odds ratio 95% CI p value
SLC2A1 rs710218 TT 2.35 1.05–5.23 0.037 *
TA+AA 1.3 0.62–2.75 0.49
rs841851 AA 3.2 1.58–6.46 0.0012 *
AG+GG 0.67 0.27–1.67 0.39
SLC23A2 rs1279683 GG 1.21 0.44–3.37 0.71
GA+AA 2.02 1.05–3.87 0.035 *

Odds ratio of APOE4 was calculated by multivariate logistic regression analysis, adjusted for effects of baseline age, follow-up period, baseline MMSE points, and sex.

* p < 0.05.