Table 2. Odds ratios of APOE4 for developing MCI and dementia, stratified by genotype of VC transporter genes.
Gene symbol | SNP ID | Genotype group | APOE4 | ||
---|---|---|---|---|---|
Odds ratio | 95% CI | p value | |||
SLC2A1 | rs710218 | TT | 2.35 | 1.05–5.23 | 0.037 * |
TA+AA | 1.3 | 0.62–2.75 | 0.49 | ||
rs841851 | AA | 3.2 | 1.58–6.46 | 0.0012 * | |
AG+GG | 0.67 | 0.27–1.67 | 0.39 | ||
SLC23A2 | rs1279683 | GG | 1.21 | 0.44–3.37 | 0.71 |
GA+AA | 2.02 | 1.05–3.87 | 0.035 * |
Odds ratio of APOE4 was calculated by multivariate logistic regression analysis, adjusted for effects of baseline age, follow-up period, baseline MMSE points, and sex.
* p < 0.05.