Table 1:
Demographics and Clinical Characteristics
| HC (n=10) | MCI (n=17) | 2-tailed p-value | |
|---|---|---|---|
| Age (mean ± SD) b | 66.7 ± 7.3 | 69.6 ± 9.1 | 0.327 |
| Female (%) c | 60.0 % | 47.1 % | 0.695 |
| Right Handedness (%) c | 90% | 88.2% | 1.000 |
| Years of Education (mean ± SD) a | 16.2 ± 2.5 | 16.9± 2.2 | 0.447 |
| IQ† (mean ± SD)b | 117.1 ± 12.4 | 118.6 ± 6.3 | 0.578 |
| ADAS-Cog Total (mean ± SD) b | 3.3 ± 1.8 | 11.9 ± 3.4 | <0.001 |
| GDS (mean ± SD) b | 1.3 ± 2.9 | 2.3 ± 2.1 | 0.024 |
| Diabetes (%) c | 0% | 11.8% | 0.516 |
| Hypertension (%) c | 20.0% | 35.3% | 0.666 |
| Hyperlipidemia (%) c | 40.0% | 76.5% | 0.101 |
| Amyloid z-score (mean ± SD) | n/a | 8.1 ± 3.2 | n/a |
| APOE4 allele ≥ 1 (%) c | 62.5% | 81.2% | 0.362 |
| BDNF-Met allele ≥ 1 (%) c | 25% | 25% | 1.000 |
| Monophasic RMT (mean ± SD) a | 57.2 ± 10.2 | 55.2 ± 9.2 | 0.623 |
| Biphasic AMT (mean ± SD) a | 40.5 ± 7.7 | 38.5 ± 6.5 | 0.493 |
| Pre-iTBS MEP (μV) (mean ± SD) b | 899.4 ± 676.6 | 1426.3 ± 1007.2 | 0.152 |
Demographic characteristics of HC and MCI participants are shown. MCI participants had impaired global cognition (ADAS-Cog) compared with controls.
†
Based on age-adjusted WTAR
a
t-test
b
Mann-Whitney U test
c
Fisher’s exact test