Supplementary Table 1. Sequences of primer used for qPCR analysis.

Gene
Homo sapiens, tryptophan 2, 3-dioxygenase 2	forward	5’-CAGTGATCCTGAAACTGCTGGTG-3’
	reverse	5’-TGCAAACTCTGGAAGCCTGATG-3’
Homo sapiens, indoleamine 2, 3-dioxygenase 1	forward	5’-TCCTGATTCCTGCAAGCCAG-3’
	reverse	5’-AGTGCCTCCAGTTCCTTTGG-3’
Homo sapiens, kynureninase	forward	5’-CAGCACTTTAATATTCCTGCCATCA-3’
	reverse	5’-GCATGTGCTAGATCAAAGCCAAC-3’
Homo sapiens, kynurenine 3-monooxygenase	forward	5’-AGATGATCACGCGATTTCAGACC-3’
	reverse	5’-CAATGCCAACGCTGCACA-3’
Homo sapiens, 3-hydroxyanthranilate 3,4-dioxygenase	forward	5’-CAGGAGCAGCTCAAAGTCATGTTC-3’
	reverse	5’-ATGACCACATCCCGGTGTTTC-3’
Homo sapiens, interleukin 6	forward	5’-AAGCCAGAGCTGTGCAGATGAGTA-3’
	reverse	5’-TGTCCTGCAGCCACTGGTTC-3’
Homo sapiens, interleukin 10	forward	5’-GAGATGCCTTCAGCAGAGTGAAGA-3’
	reverse	5’-AAGGCTTGGCAACCCAGGTA-3’
Homo sapiens, matrix metalloproteinase-2	forward	5’-CTTCCAAGTCTGGAGCGATGTG-3’
	reverse	5’-ATGAGCCAGGAGTCCGTCCTTA-3’
Homo sapiens, matrix metalloproteinase-9	forward	5’-TGGCACCACCACAACATCAC-3’
	reverse	5’-GCAAAGGCGTCGTCAATCA-3’
Homo sapiens, tissue factor	forward	5’-TGACCTCACCGACGAGATTGTGAA-3’
	reverse	5’-TCTGAATTGTTGGCTGTCCGAGGT-3’
Homo sapiens, human β-actin	forward	5’-TGGCACCCAGCACAATGAA-3’
	reverse	5’-TAAGTCATAGTCCGCCTAGAAGCA-3’