Figure 3.

Baicalin prevents the colocalization of TXNIP and NLRP3 in Mtb-infected macrophages. (a, b) Confocal microscopy of RAW264.7 cells with different treatments immunostained with anti-TXNIP (red), anti-NLRP3 (green), and DAPI (blue). Mean ± SD of colocalization of TXNIP and NLRP3, TXNIP and NLRP3 florescence intensity in three independent pictures was shown as scatter plot and error bar (n = 3). Kruskal-Wallis H rank and inspection was used as the statistical analysis method. According to the statistical results of Kruskal-Wallis H rank sum test, p < 0.05. The difference between the three groups was statistically significant.