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. 2021 Nov 8;2021:1805147. doi: 10.1155/2021/1805147

Figure 4.

Figure 4

Baicalin attenuates TXNIP via inhibiting endoplasmic reticulum stress in Mtb-infected macrophages. (a, c) Levels of BIP and CHOP protein were tested by western blotting measurement in RAW264.7 cells. (b, d) Levels BIP and CHOP protein were measured by western blotting in primary peritoneal macrophage cells. (e) Transfection efficiency of siRNAs was measured by western blotting analysis in RAW264.7 cells. (f) Western blotting analysis of TXNIP expression after siRNAs of IRE1α, PERK, and ATF6, respectively, in RAW264.7 cells. Data are shown as mean ± SD of three independent experiments. p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001; NS: nonsignificant.