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. 2021 Nov 16;41(5):1349–1357. doi: 10.1007/s10067-021-05980-5

Table 1.

Clinical characteristics of flares post SARS-CoV-2 immunization

Total 20a
Age-years 38.65 ± 14.13
Sex-no. (%)

Female

Male

18 (90%)

2 (10%)

Length of illness (SLE)-years 7.04 ± 4.85
SLE treatmentb

Prednisone

Hydroxychloroquine

azathioprine

Mycophenolate

Methotrexate

Leflunomide

No treatment

16 (80%)

11 (55%)

10 (50%)

3 (15%)

3 (15%)

1 (5%)

3 (15%)

SLE outbreak in the past 6 months 8 (40%)
Confirmed COVID-19 history 13 (65%)
Flare episodes after immunization

1st dose

2nd dose

1st and 2nd doses

9 (45%)

18 (90%)

7 (35%)

Type of flare 1era dosis 2da dosis

Arthritis

Malar erythema

Alopecia

Lupus pneumonitis

leukopenia

Myopericarditis

6 (30%)

1 (5%)

-

1 (5%)

1 (5%)

1 (5%)

17 (85%)

4 (20%)

1 (5%)

-

-

-

Hospitalization for flare 2

a20 patients presented post-immunization flare; however, there were 27 flare episodes (given that 7 patients had flare episodes in the 1st and 2nd doses)

b15 patients use 2 or more drugs