Table 2.
Biomarkers of Thrombo-Inflammation and Black Race
| Biomarker, β (95%CI) |
|||||||
|---|---|---|---|---|---|---|---|
| SuPAR | C-reactive protein | Lactate dehydrogenase | Interleukin-6 | Procalcitonin | Ferritin | D-dimer | |
| Black race | −1.00 (−1.93 to −0.07) | −7.74 (−13.86 to −1.61) | 73 (31-114) | 19.93(−81.70 to 121.56) | 0.75 (−4.69 to 6.18) | 439 (187-691) | −0.17 (−5.87 to 5.54) |
| Age, per 1 year | −0.03 (−0.06 to 0.00) | −0.20 (−0.41 to 0.02) | −1 (−3 to 0) | −2.01 (−5.93 to 1.91) | 0.03 (−0.17 to 0.22) | −4 (−13 to 5) | 0.09 (−0.11 to 0.29) |
| Male gender | −0.67 (−1.52 to 0.19) | −5.09 (−10.54 to 0.35) | −42 (−80 to −5) | −78.68 (−178.31 to 20.95) | −0.77 (−5.69 to 4.14) | −522 (−747 to −297) | −3.68 (−8.74 to 1.38) |
| BMI, per 1 kg/m2 | 0.07 (0.02-0.12) | 0.05 (−0.29 to 0.39) | 2 (0-5) | 0.30 (−6.17 to 6.76) | −0.16 (−0.46 to 0.15) | 0 (−14 to 14) | 0.39 (0.08-0.71) |
| Diabetes mellitus | 0.54 (−0.39 to 1.48) | 6.20 (0.19-12.21) | −12 (−53 to 30) | 81.59 (−26.96 to 190.15) | −1.62 (−7.03 to 3.80) | 121 (−127 to 367) | −1.47 (−7.04 to 4.09) |
| Hypertension | −0.68 (−1.69 to 0.33) | −0.79 (−7.19 to 5.61) | −54 (−98 to −9) | −46.49 (−165.83 to 72.86) | −3.51 (−9.30 to 2.27) | −204 (−470 to 62) | −3.53 (−9.51 to 2.45) |
| Coronary artery disease | 1.03 (−0.20 to 2.26) | −8.49 (−16.49 to −0.50) | −37 (−92 to 18) | −33.86 (−174.29 to 106.57) | −0.79 (−7.85 to 6.26) | −113 (−439 to 213) | −0.42 (−7.84 to 7.01) |
| Heart failure | 0.62 (−0.71 to 1.94) | 0.46 (−8.23 to 9.15) | 16 (−43 to 74) | 34.63 (−113.93 to 183.19) | −2.34 (−10.10 to 5.41) | −242 (−592 to 109) | −0.68 (−8.58 to 7.22) |
| Admission eGFR | −0.06 (−0.08 to −0.05) | −0.10 (−0.20 to 0.01) | −1 (−2 to 0) | −1.00 (−2.79 to 0.79) | −0.06 (−0.15 to 0.03) | −8 (−12 to −3.6) | 0.00 (−0.09 to 0.10) |
BMI = body mass index; CI = confidence interval; eGFR = estimated glomerular filtration rate.