Table 2.
Ovarian stimulation variables and IVF results of HBV-positive and HBV-negative groups.
|
HBV group
(n = 99) |
Control group
(n = 198) |
P-value | |
|---|---|---|---|
| Female age (years) | 33.0 ± 4.0 | 33.0 ± 3.9 | 0.959a |
| Female BMI (kg/m2) | 23.2 ± 3.4 | 23.3 ± 3.3 | 0.836a |
| Duration of subfertility (years) | 4.4 ± 2.9 | 4.5 ± 3.0 | 0.847a |
| Primary infertility (n, %) | 47/99 (47.4%) | 104/198 (52.5%) | 0.411b |
| Causes of subfertility (n, %) | |||
| Male factor | 11/99 (11.1%) | 29/198 (14.6%) | 0.400b |
| Tubal blockage | 65/99 (65.6%) | 113/198 (57.0%) | 0.154b |
| Ovulation failure | 19/99 (19.1%) | 48/198 (24.2%) | 0.326b |
| Endometriosis | 4/99 (0.04%) | 15/198 (0.07%) | 0.240b |
| Unexplained | 14/99 (14.1%) | 34/198 (17.1%) | 0.503b |
| Total dose of gonadotropin used (IU) | 1,941.5 ± 744.2 | 1,993.3 ± 768.0 | 0.576a |
| Duration of gonadotropin stimulation (d) | 9.7 ± 3.1 | 9.8 ± 2.9 | 0.808a |
| Serum E2 level on the day of hCG injection (pg/ml) | 2,377.8 ± 1,323.9 | 2,469.1 ± 1,319.0 | 0.575a |
| Serum P level on the day of hCG injection (ng/ml) | 0.7 ± 0.3 | 0.7 ± 0.3 | 0.988a |
| Endometrial thickness on the day of hCG injection (mm) | 10.3 ± 2.2 | 10.5 ± 2.0 | 0.434a |
| 2PN fertilization rate (%) | 490/745 (65.7%) | 1,030/1,516 (67.9%) | 0.301b |
| High-grade embryo rate (%) | 222/447 (49.6%) | 468/894 (52.3%) | 0.353b |
| Implantation rate (%) | 81/189 (42.8%) | 134/373 (35.9%) | 0.110b |
| Clinical pregnancy rate (n, %) | 58/99 (58.5%) | 106/198 (53.5%) | 0.409b |
| Abortion rate (n, %) | 10/58 (17.2%) | 18/106 (16.9%) | 0.966b |
Values are presented as mean ± standard deviation.
P-values were obtained using aTwo-sided t-test or bChi-squared test.
HBV, Hepatitis B virus; BMI, body mass index; E2, estradiol; P, progesterone; hCG, human chorionic gonadotrophin; 2PN, two-pronuclear.