Table 1.
Acute coronary syndrome (ACS) cohort | Type and unit | Overall ACS cohort | Substantial myocardial injury | Minor myocardial Injury | p–value |
---|---|---|---|---|---|
n = 82 | n = 42 | n = 40 | |||
Age | Median (IQR), [years] | 69.52 (58.89–78.47) | 71.26 (57.56–80.47) | 68.61 (63.5–75.43) | 0.702 |
Male sex | n (%) | 51 (62.2) | 26 (61.9) | 25 (62.5) | 1 |
Final diagnosis | |||||
Acute myocardial infarction | n (%) | 48 (58.54) | 38 (90.48) | 10 (25) | <0.001 |
Cardiovascular risk factors | |||||
Arterial hypertension | n (%) | 58 (79.45) | 26 (76.47) | 32 (82.05) | 0.091 |
Dyslipidemia | n (%) | 39 (55.71) | 19 (55.88) | 20 (55.56) | 0.825 |
Diabetes mellitus | n (%) | 21 (28.77) | 9 (26.47) | 12 (30.77) | 0.452 |
Smoking | n (%) | 29 (50.88) | 14 (53.85) | 15 (48.39) | 0.818 |
Family history | n (%) | 15 (28.3) | 7 (26.92) | 8 (29.63) | 0.779 |
History | |||||
Known coronary artery disease | n (%) | 30 (50.85) | 11 (44) | 19 (55.88) | 0.066 |
Laboratory analyses | |||||
eGRF | median (IQR), [ml/min/1.73 m2] | 86.17 (58.28–104.84) | 87.13 (55.52–104.45) | 83.12 (66.54–103.66) | 0.612 |
Creatinine | median (IQR), [mg/dl] | 0.87 (0.75–1.11) | 0.86 (0.73–1.12) | 0.87 (0.78–1.07) | 0.545 |
hs-cTnI | median (IQR), [pg/mL] | 28.2 (4–531.35) | 525.6 (214.03–2,986.82) | 4 (2.55–7.25) | <0.001 |
Cholesterol | mean ± SD, [mg/dl] | 201.91 ± 45.52 | 211 ± 45.93 | 184.88 ± 42.25 | 0.19 |
C-reactive protein | median (IQR), [mg/dl] | 0.3 (0.2–1.4) | 0.4 (0.18–1.52) | 0.3 (0.2–1) | 0.82 |
Data are shown stratified according to the extent of myocardial injury defined by high sensitivity cardiac troponin I values (99th percentile cut-off).
Data are presented as percentage, mean, or median as appropriate. eGFR denotes estimated glomerular filtration rate, hs-cTnI denotes high sensitivity cardiac troponin I.