Table 1.

Participant characteristics, psychiatric diagnosis and psychotropic medication

	Diagnostic group			Comparison
				TDs-22q11DS		TDs-ASD		22q11DS-ASD
	TDs	22q11DS	ASD	Statistical test	p value	Statistical test	p value	Statistical test	p value
N	33	24	20
Gender [female (%)]	15 (45%)	8 (50%)	7 (35%)	χ2 = 0.848	0.357	χ2 = 0.561	0.454	χ2 = 0.013	0.908
Age [mean (SD)]	18.60 (3.80)	18.09 (4.02)	17.43 (4.13)	t = 0.490	0.626	t = 1.050	0.299	t = 0.533	0.597
Full scale IQ [mean (SD)]	109.16 (13.22)	73.00 (16.49)	101.75 (19.47)	t = 8.906	0.000	t = 1.615	0.113	t = -5.242	0.000
Psychiatric diagnosis [N (%)]
Simple phobia		5 (20.83%)	3 (15%)
Agoraphobia		0	2 (10%)
Social phobia		1 (4.16%)	4 (20%)
Generalized anxiety		5 (20.83%)	1 (5%)
Attention deficit disorder		6 (25%)	4 (20%)
Persistant depressive disorder		0	2 (10%)
Major depressive episode		0	2 (10%)
Psychosis		0	0
Obsessive–compulsive disorder		0	0
ADOS-2 module 3 (N = 7) (mean)
ADOS-2 total score			11.43
ADOS-2 SA score			8.28
ADOS-2 RRB score			3.14
ADOS-2 module 4 (N = 13) (mean)
ADOS-2 total score			12.85
ADOS-2 SA score			9.38
ADOS-2 RRB score			3.46
ADI-R (N = 9) (mean)
ADI-R domain A			18
ADI-R domain B			13.33
ADI-R domain C			5.77
SCQ (N = 70) (mean)
SCQ total score	3.07	8.87	18.77
Psychotropic medication
Total [N(%)]		12 (50%)	6 (30%)
Categories
Psychostimulant		8 (33.33%)	2 (10%)
Antidepressants		4 (16.66%)	1 (5%)
Neuroleptics		4 (16.66%)	2 (10%)
Antiepilecptics		2 (8.33%)	0
Anxiolytics		2 (8.33%)	1 (5%)

Significant p-values at the 0.05 level are displayed in bold

TDs had been screened for psychiatric diagnostics conforming to our exclusion criterias