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Effects of runcaciguat in conscious ZDF rats treated with either vehicle or runcaciguat (140 ppm) on mean arterial pressure (MAP) measured by tail-cuff at the beginning of the study (week 0) and after 5, 9, 13, 18, 20, 23, 25, 28, 32, 38, and 42 weeks of treatment. Data are mean ± SEM; N = 20/group (study start). Significant changes were determined by t-test with * for p < 0.05
