Table 1.
Inhibitory activity of niraparib on individual PARP isoforms [7]
| IC50 (nM) | |
|---|---|
| PARP1 | 3.8 |
| PARP2 | 2.1 |
| PARP3 | 1300 |
| V-PARP | 330 |
IC50 half-maximal inhibitory concentration
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