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. 2021 Oct 18;9(2):647–657. doi: 10.1007/s40487-021-00171-3
Non-small cell lung cancer (NSCLC) patients with and without response to PD-I immunotherapy have different diversity and composition of gut microbiota.
The relative abundances of Escherichia-Shigella, Akkermansia and Olsenella might have contributed to the different composition of gut microbiota.
Escherichia-Shigella and Akkermansia might have specific effects on the PD-1 inhibitory immunotherapy for NSCLC, and a possible association with interleukin-12 (IL-12) and interferon gamma (IFN-γ).