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. 2021 Nov 15;11:22242. doi: 10.1038/s41598-021-01473-2

Table 2.

Grade 2 or higher adverse events possibly, probably, or definitely related to T-VEC.

Adverse event Grade 2, n (%) Grade 3, n (%)
General disorders and injection site conditions
 Fatigue 4 (44)
 Fever 2 (22)
 Injection site reaction 7 (78)
 Tumor/injection site pain 5 (56)
Gastrointestinal disorders
 Constipation 1 (11)
 Nausea 2 (22)
 Vomiting 2 (22)
Tumor/injection site infection 1 (11) 2 (22)
Myalgia 1 (11)
Pain in extremity 1 (11)
Pruritus 1 (11)
Lymphedema 2 (22) 1 (11)
Neutrophil count decreased 1 (11)