Table 4.

Extrapolation of average monthly all-cause healthcare costs to estimate cumulative costs incurred following the index date^a

Month post-TCE LOT initiation	All-cause total healthcare costs
1	$34,578
2	$69,156
3	$103,734
4	$138,312
5	$172,890
6	$207,468
7	$242,046
8	$276,624
9	$311,202
10	$345,780
11	$380,358
12	$414,936
13	$449,514
14	$484,092
15	$518,670
16	$553,248
17	$587,826
18	$622,404
19	$656,982
20	$691,560
21	$726,138
22	$760,716
23	$795,294
24	$829,872
25	$864,450
26	$899,028
27	$933,606
28	$968,184
29	$1,002,762
30	$1,037,340
31	$1,071,918
32	$1,106,496
33	$1,141,074
34	$1,175,652
35	$1,210,230
36	$1,244,808
37	$1,279,386
38	$1,313,964
39	$1,348,542
40	$1,383,120

LOT line of therapy, TCE triple class exposure

^a Index date, defined as the initiation date of first LOT post-TCE

Italicized costs are projected based on the dataset of patients included in this study with an average follow-up of 20.9 months