Table 3.

Correlation between the extent of TAM infiltration, MVD value, PTEN/PI3K/p-AKT expression, and clinicopathological parameters.

Variable	Cases(N)	Number of M1 TAMs				Number of M2 TAMs				Number of MVD				Expression of PTEN				Expression of PI3K				Expression of p-AKT
		High	Low	χ2	p	High	Low	χ2	p	High	Low	χ2	p	High	Low	χ2	p	High	Low	χ2	p	High	Low	χ2	p
Gender
Male	32	25	7	2.079	0.149	5	27	0.033	0.855	26	6	0.397	0.529	10	22	0.083	0.774	23	9	1.707	0.191	25	7	2.079	0.149
Female	17	16	1			3	14			15	2			6	11			15	2			16	1
Age (years)
<60	13	10	3	0.590	0.442	4	9	2.702	0.100	10	3	0.590	0.442	6	7	1.467	0.226	11	2	0.507	0.476	11	2	0.011	0.915
≥60	36	31)	5			4	32			31	5			10	26			27	9			30	6
Tumor diameter (cm)
<3	17	12	5	3.263	0.071	5	12	3.263	0.071	11	6	6.855	0.009*	10	7	8.107	0.004*	11	6	2.467	0.116	11	6	6.855	0.009*
≥3	32	29	3			3	29			30	2			6	26			27	5			30	2
Histology grade
G1–G2	36	29	7	0.966	0.326	7	29	0.966	0.326	30	6	0.011	0.915	13	23	0.738	0.390	27	9	0.507	0.476	30	6	0.011	0.915
G3	13	12	1			1	12			11	2			3	10			11	2			11	2
Depth of invasion
T1–T2	24	16	8	9.959	0.002*	7	17	5.677	0.017*	17	7	5.677	0.017*	13	11	9.900	0.002*	14	10	9.979	0.002*	16	8	9.959	0.002*
T3–T4	25	25	0			1	24			24	1			3	22			24	1			25	0
Lymph node status
N−	32	24	8	5.079	0.038*	8	24	5.079	0.038*	24	8	5.079	0.038*	15	17	8.483	0.004*	22	10	4.104	0.043*	24	8	5.079	0.038*
N+	17	17	0			0	17			17	0			1	16			16	1			17	0
Pathological stage
I-II	32	24	8	5.079	0.038*	8	24	5.079	0.038*	24	8	5.079	0.038*	15	17	8.483	0.004*	22	10	4.104	0.043*	24	8	5.079	0.038*
III-IV	17	17	0			0	17			17	0			1	16			16	1			17	0

N⁺, Lymph node metastasis; N⁻, No lymph node metastasis; MVD, Microvessel density. ^*p < 0.05.