Table 1.
Relative expression of mitochondrial and glycolysis-associated genes in patients with high GMFB expression.
| Description | Query | Statistic | P-value | FDR (BH) |
|---|---|---|---|---|
| Mitochondrial protein synthesis | MRPL1 | -0.141321338 | 0.007160143 | 0.016746243 |
| MRPL10 | -0.105032788 | 0.046127911 | 0.083444214 | |
| MRPL11 | -0.311787832 | 1.40402E-09 | 1.36064E-08 | |
| MRPL12 | -0.411325456 | 3.58815E-16 | 1.52363E-14 | |
| MRPL14 | -0.382101015 | 5.3916E-14 | 1.32397E-12 | |
| MRPL15 | -0.119926057 | 0.022671632 | 0.045620446 | |
| MRPL16 | -0.269955944 | 1.90488E-07 | 1.2005E-06 | |
| MRPL17 | -0.298656993 | 7.14778E-09 | 6.03425E-08 | |
| MRPL19 | 0.157548668 | 0.002683783 | 0.006989346 | |
| MRPL2 | -0.376971399 | 1.23596E-13 | 2.79072E-12 | |
| MRPL20 | -0.377361436 | 1.161E-13 | 2.63641E-12 | |
| MRPL21 | -0.296536472 | 9.22667E-09 | 7.60237E-08 | |
| MRPL22 | -0.340013844 | 3.20959E-11 | 4.42054E-10 | |
| MRPL23 | -0.361800315 | 1.32141E-12 | 2.39235E-11 | |
| MRPL24 | -0.32727754 | 1.85288E-10 | 2.16296E-09 | |
| MRPL32 | -0.264832174 | 3.2938E-07 | 1.99866E-06 | |
| MRPL34 | -0.364195064 | 9.16604E-13 | 1.70919E-11 | |
| MRPL36 | -0.319586768 | 5.13832E-10 | 5.49274E-09 | |
| MRPL37 | -0.256312337 | 7.98478E-07 | 4.44927E-06 | |
| MRPL38 | -0.452159392 | 1.36218E-19 | 1.48969E-17 | |
| MRPL4 | -0.318917541 | 5.60762E-10 | 5.93704E-09 | |
| MRPL41 | -0.504373553 | 1.08008E-24 | 5.00226E-22 | |
| MRPL46 | -0.229639252 | 1.04789E-05 | 4.68855E-05 | |
| MRPL47 | -0.261962532 | 4.45388E-07 | 2.62279E-06 | |
| MRPL49 | 0.145262194 | 0.0056907 | 0.013647675 | |
| MRPL53 | -0.437150183 | 2.79E-18 | 2.09671E-16 | |
| MRPL54 | -0.475611761 | 8.9333E-22 | 1.83209E-19 | |
| MRPL55 | -0.407366684 | 7.28546E-16 | 2.89601E-14 | |
| MRPS12 | -0.419680399 | 7.8018E-17 | 4.04617E-15 | |
| MRPS14 | -0.1433601 | 0.006362258 | 0.015065919 | |
| MRPS15 | -0.404028697 | 1.31418E-15 | 4.81987E-14 | |
| MRPS16 | -0.350958594 | 6.66495E-12 | 1.0501E-10 | |
| MRPS17 | -0.268732399 | 2.17326E-07 | 1.35505E-06 | |
| MRPS18A | -0.273086412 | 1.35554E-07 | 8.82209E-07 | |
| MRPS18B | -0.115880152 | 0.027700048 | 0.054056487 | |
| MRPS18C | -0.241995373 | 3.29881E-06 | 1.6322E-05 | |
| MRPS2 | -0.404723616 | 1.16293E-15 | 4.33704E-14 | |
| MRPS22 | -0.181553225 | 0.000527481 | 0.00163143 | |
| MRPS24 | -0.534918562 | 4.13643E-28 | 4.11885E-25 | |
| MRPS25 | -0.45798162 | 4.0535E-20 | 4.98305E-18 | |
| MRPS26 | -0.438152315 | 2.29116E-18 | 1.76172E-16 | |
| MRPS28 | -0.110719774 | 0.035478952 | 0.066801865 | |
| MRPS28 | -0.110719774 | 0.035478952 | 0.066801865 | |
| MRPS30 | -0.136957465 | 0.009175224 | 0.020847072 | |
| MRPS31 | -0.103676942 | 0.049029226 | 0.087894232 | |
| MRPS33 | -0.363111917 | 1.08192E-12 | 1.98585E-11 | |
| MRPS34 | -0.387347676 | 2.27307E-14 | 6.07627E-13 | |
| MRPS5 | -0.358159625 | 2.29094E-12 | 3.95922E-11 | |
| MRPS6 | -0.176539551 | 0.000754091 | 0.002254576 | |
| MRPS7 | -0.291364752 | 1.70489E-08 | 1.33149E-07 | |
| MRPS9 | -0.249646084 | 1.56238E-06 | 8.2184E-06 | |
| Mitochondrial dynamics | MTP18(MTFP1) | -0.22064897 | 2.34E-05 | 9.74E-05 |
| FIS1 | -0.399647594 | 2.82E-15 | 9.49E-14 | |
| Mitochondrial protein import | TOMM40 | -0.277369089 | 8.45E-08 | 5.78E-07 |
| TOMM7 | -0.423363936 | 3.93E-17 | 2.13E-15 | |
| Mitophagy | PINK1 | -0.159223311 | 0.002412305 | 0.006368958 |
| Glucose metabolism | FBP1 | -0.218488252 | 2.82E-05 | 0.000115938 |
| TPI1 | -0.245741921 | 2.29E-06 | 1.17E-05 | |
| PCK1 | -0.191431015 | 0.00025373 | 0.00084683 |
MRPLs, Mitochondrial Ribosomal Protein Ls; MRPSs, Mitochondrial Ribosomal Protein Ss; MTP18(MTFP1), Mitochondrial Fission Process 1; FIS1,Fission, Mitochondrial 1; TOMMs, Translocase Of Outer Mitochondrial Membranes; PINK1, PTEN Induced Kinase 1; FBP1, Fructose-Bisphosphatase 1; TPI1, Triosephosphate Isomerase 1; PCK1,Phosphoenolpyruvate Carboxykinase 1.