Table 1.
BPV types and their associated lesions at multiple anatomic sites.
| BPV type | Genus | Tissue tropism | Anatomical distribution | Lesions | Early genes | References |
|---|---|---|---|---|---|---|
| BPV 1 | Deltapapillomavirus | Epithelium and Dermis | Skin, Bladder, Udder | Fibropapillomas Urinary bladder cancer |
E1, E2, E4, E5, E6, E7, | (55) |
| BPV 2 | Deltapapillomavirus | Epithelium and Dermis | Skin, Bladder, Udder | Fibropapillomas Urinary bladder cancer |
E1, E2, E3, E4, E5, E6, E7, E8, | (76) |
| BPV 3 | Xipapillomavirus | Epitheliotropic | Skin, Teat, Udder | Epithelial papillomas | E1, E2, E4, E7, E8, | (42) |
| BPV 4 | Xipapillomavirus | Epitheliotropic | Skin, Upper digestive tract | Epithelial papillomas Upper digestive carcinomas |
E1, E2, E3, E4, E7, E8 | (77) |
| BPV 5 | Epsilonpapillomavirus | Epithelium and Dermis | Teat | Epithelial papillomas and fibropapillomas | E1, E2, E6, E7 | (78, 79) |
| BPV 6 | Xipapillomavirus | Epitheliotropic | Skin, Teat | Epithelial papillomas | E1, E2, E4, E7, E8, | (80) |
| BPV 7 | Dyoxypapillomavirus | Epitheliotropic | Skin, Teat | Epithelial papillomas | E1, E2, E4, E6, E7 | (81) |
| BPV 8 | Epsilonpapillomavirus | Epithelium and Dermis | Skin, Teat | Epithelial papillomas and fibropapillomas | E1, E2, E4, E5, E6, E7 | (58) |
| BPV 9 | Xipapillomavirus | Epitheliotropic | Skin, Teat, Udder | Epithelial papillomas | E1, E2, E5, E7 | (82) |
| BPV 10 | Xipapillomavirus | Epitheliotropic | Skin, Teat, Udder | Epithelial papillomas | E1, E2, E4, E5, E7 | (82) |
| BPV 11 | Xipapillomavirus | Epitheliotropic | Teat | Epithelial papillomas Fibropapillomas |
E1, E2, E4, E7, E10 | (83) |
| BPV 12 | Xipapillomavirus | Epitheliotropic | Tongue | Epithelial papillomas | E1, E2, E4, E7, E8 | (84) |
| BPV 13 | Deltapapillomavirus | Epithelium and Dermis | Skin | Fibropapillomas | E1, E2, E4, E5, E6, E7 | (85) |
| BPV 14 | Deltapapillomavirus | Epithelium and Dermis | Skin, bladder | Fibropapillomas | E1, E2, E5, E6, E7 | (65, 86) |
| BPV 15 | Xipapillomavirus | Epitheliotropic | Skin | Epithelial papillomas | E1, E2, E5, E7 | (87) |
| BPV 16 | Dyoxypapillomavirus | Epithelium and Dermis | Skin | Fibropapillomas and cutaneous papillomas | E1, E2, E4, E6, E7 | (88) |
| BPV 17 | Xipapillomavirus | Epitheliotropic | Skin | Epithelial papillomas | E1, E2, E6, E7 | (88) |
| BPV 18 | Dyoxypapillomavirus | Epitheliotropic | Skin | Epithelial papillomas |
E1, E2, E6, E7 | (88) |
| BPV 19 | Unassigned genus | Epitheliotropic | Skin | Epithelial papillomas | E1, E2, E6, E7 | (88) |
| BPV 20 | Xipapillomavirus | Epitheliotropic | Skin | Epithelial papillomas | E1, E2, E4, E6, E7 | (88) |
| BPV 21 | Unassigned genus | Epitheliotropic | Skin | Epithelial papillomas | E1, E2, E6, E7 | (88) |
| BPV 22 | Dyoxypapillomavirus | Vaginal mucosa | Vagina | Vulvovaginitis | E1, E2, E6, E7 | (70) |
| BPV 23 | Xipapillomavirus | Epitheliotropic | Skin | Epithelial papillomas | E1, E2, E4, E7, E8 | (56) |
| BPV 24 | Xipapillomavirus | Epitheliotropic | Skin | Epithelial papillomas | E1, E2, E4, E5, E7 | (89) |
| BPV 25 | Epsilonpapillomavirus | Epitheliotropic | Skin | Epithelial papillomas | E1, E2, E6, E7 | (90, 91) |
| BPV 26 | Xipapillomavirus | Not reported | Not reported | Papillomas | E1, E2, E4, E5, E7, E8 | (92) |
| BPV 27 | Unclassified | Not reported | Genitalia | Not reported | E1, E2, E6, E7 | (93) |
| BPV 28 | Xipapillomavirus | Epitheliotropic | Vulva | Papillomas | E1, E2, E4, E7, E10 | (94) |
| BPV 29 | Xipapillomavirus | Epitheliotropic | Vulva | Papillomas | E1, E2, E4, E7, E10 | (94) |