Table 3. Relationship of various proteins in plasma and amniotic fluid with the presence of MIAC, IAI, and microbial-associated IAI, analyzed using multiple logistic regression.

Predictors	MIACa		IAIb		Microbial-associated IAIb
	OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value
Plasma LBP, µg/mL	1.132 (1.033–1.242)	0.008	1.178 (1.066–1.302)	0.001	1.148 (1.043–1.264)	0.005
AF LBP, µg/mL	3.939 (1.197–12.963)	0.024	37.140 (5.039–273.746)	< 0.001	9.167 (2.341–35.900)	0.001
AF PTX3, ng/mL	1.120 (1.067–1.174)	< 0.001	1.390 (1.210–1.597)	< 0.001	1.132 (1.077–1.189)	< 0.001
AF resistin, ng/mL	1.022 (1.015–1.028)	< 0.001	1.034 (1.022–1.047)	< 0.001	1.006 (1.003–1.009)	< 0.001
Plasma IGFBP-3, ng/mL			0.997 (0.994–0.999)	0.007
AF IGFBP-3, ng/mL					0.998 (0.996–0.999)	< 0.001
Serum CRP, mg/dL	1.328 (1.023–1.724)	0.033	2.405 (1.521–3.803)	< 0.001	1.544 (1.162–2.050)	0.003
AF IL-8, ng/mL	1.186 (1.104–1.273)	< 0.001	2.426 (1.685–3.493)	< 0.001	1.233 (1.140–1.333)	< 0.001

MIAC = microbial invasion of the amniotic cavity, IAI = intra-amniotic inflammation, LBP = lipopolysaccharide binding protein, AF = amniotic fluid, PTX3 = pentraxin 3, IGFBP = insulin-like growth factor-binding protein, CRP = C-reactive protein, IL = interleukin.

^aAdjustment for gestational age at sampling; ^bAdjustment for gestational age at sampling and parity.

Significant findings (P < 0.05) are indicated in bold fonts.