Table 2:
Summary of socio-demographic and vascular risk data for SVD and control cohorts
SVD cohorts | Control cohorts | |||
---|---|---|---|---|
cohorts (n=89) | mean (SD or 95% CI) | cohorts (n=71) | mean (SD or 95% CI) | |
mean age* | 88 | 69.3 (67.8, 70.9) | 70 | 66.4 (64.6, 68.2) |
% female | 76 | 49.0 (15.9) | 63 | 50.9 (15.0) |
mean years education* | 67 | 10.3 (9.7, 10.9) | 53 | 10.8 (10.1, 11.6) |
% hypertension | 48 | 66.7 (23.0) | 34 | 37.8 (20.7) |
% diabetes | 45 | 25.5 (13.7) | 31 | 17.1 (13.5) |
% hypercholesterolemia | 5 | 55.1 (20.0) | 4 | 35.1 (12.3) |
% history of smoking | 28 | 28.3 (16.1) | 16 | 25.6 (16.9) |
Mean age and mean years of education were calculated using random effects meta-analysis in the meta package in R version 3.6.1 (Schwarzer G. “meta: An R package for meta-analysis.” R News 2007, 7(3), 40–45). Only studies that presented group level data for age and years of education as mean and standard deviation were included in these meta-analyses. We did not test for differences in age, sex, level of education, or vascular risk factors between the SVD and control groups as some studies only reported these data for the SVD group, therefore, comparisons would not include all participants contributing cognitive data to the meta-analyses.