Table 2.
Reproductive outcomes after breast cancer treatment
| Reproductive outcomes | ART group (n = 22) | Non-ART group (n = 146) |
|---|---|---|
| Median age at the time of pregnancy, years (IQR) | 39.7 (35.3-41.4) | 35.4 (32.7-38.0) |
| Median time from breast cancer diagnosis to conception, years (IQR) | 5.4 (2.4-6.7) | 3.5 (2.3-5.2) |
| Pregnancy outcomes, n (%) | ||
| Live birth | 18 (81.8) | 113 (77.4) |
| Ongoing | 1 (4.6) | 4 (2.7) |
| Induced abortion | 0 (0.0) | 13 (8.9) |
| Miscarriage | 3 (13.6) | 15 (10.3) |
| Unknown | 0 (0.0) | 1 (0.7) |
| Timing of delivery, n (%) | ||
| At term (≥37 weeks) | 11 (61.1) | 84 (74.3) |
| Preterm (<37 weeks) | 3 (16.7) | 7 (6.2) |
| Unknown | 4 (22.2) | 22 (19.5) |
| Pregnancy complications, n (%) | ||
| None | 10 (45.5) | 82 (56.2) |
| Delivery complications | 5 (22.7) | 6 (4.1) |
| Congenital abnormalities | 1 (4.5) | 3 (2.0) |
| No. missing | 6 (27.3) | 55 (37.7) |
| Breast feeding, n (%) | ||
| Yes | 2 (9.1) | 28 (19.2) |
| No | 8 (36.4) | 43 (29.4) |
| Unknown | 12 (54.5) | 75 (51.4) |
| Median duration (years) | 0 | 1 |
| Type of ART, n (%) | Not applicable | |
| Embryo transfer under HRT following oocyte and/or embryo cryopreservation at diagnosis | 4 (18.2) | |
| Embryo transfer under HRT following oocyte donation | 5 (22.7) | |
| Ovarian stimulation for IVF/ICSI after cancer treatment | 7 (31.8) | |
| Ovulation induction | 1 (4.5) | |
| Unknown | 5 (22.7) |
ART, assisted reproductive technologies; HRT, hormonal replace therapy; ICSI, intracytoplasmic sperm injection; IQR, interquartile range; IVF, in vitro fertilization.