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. 2021 Nov 2;11:772789. doi: 10.3389/fonc.2021.772789

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Copyright © 2021 Mantovani, Gastino, Cerrato, Badellino, Ricardi and Levis

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MRI findings presenting the evolution of radionecrosis (RN) within a timeframe of 18 months from the end of radiosurgery (SRS) in a single right temporal BM from NSCLC. The first images on the left (axial and coronal) represent the lesion before focal treatment. Serial follow up images show an initial shrinkage of the treated lesion followed by a significant and continuous increase of the necrotic component. The latest images on the right (axial and coronal) refers to the situation 18 months after SRS, with a clear reduction of the necrotic component, which allows a differential diagnosis with a relapse.