Table 2.

Gut microbiota proportions in ocular diseases

Disease	Findings
Dry eye in Sjögren's	Mice: increased numbers of Enterobacter, Escherichia/Shigella, Pseudomonas, and decreased numbers of Clostridium. [52] Human: increased numbers of Bacteroides*, Parabacteroides*, Actinobacteria, Pseudobutyrivibrio, Escherichia/Shigella, Blautia, Streptococcus, anddecreased numbers of Firmicutes, Faecalibacterium, Prevotella, Viellonella. [52,53]
Uveitis	Mice: decreased numbers of Rikenellaceae and increased numbers of Paraprevotella.[25] Human: increased numbers of Fusobacterium and Enterobacteriaceace.[51]
Diabetic retinopathy	Mice: increased numbers of Firmicutes and decreased Bacteroidetes.[54] Human: decreased numbers of Bacteroides and Lactobacillus. [55,56]
Age-related macular degeneration	Mice: increased numbers of Firmicutes and Clostridia, and decreased numbers of Bacteroidetes and Erysipelotrichi.[30] Human: increased numbers of Ruminococcaceae, Prevotella, Anaerotruncus, Oscillibacter, Ruminiococcus torques, and Eubacterium ventriosum.[51,57]
Bacterial keratitis	Human: increased numbers of Proteobacteria and Firmicutes.[58]
*There were discrepancies between studies