Table 3. Hazard ratios (95% confidence intervals) of incident endometrial cancer according to weight change since age 20.

	Weight change since age 20, kg			P for trend
	<−5	−5 to <+5	≥+5
Number at risk	11,259	11,648	10,894
Person years	145,986	161,502	148,047
Number of cases	17	22	40
Model 1a	0.80 (0.42–1.54)	1	2.00 (1.19–3.36)	0.001
Model 2b	0.78 (0.30–2.02)	1	1.96 (1.12–3.40)	0.001

^aModel 1 adjusted for age.

^bModel 2 adjusted further for body mass index at age 20, history of diabetes, history of hypertension, age at menarche, menstrual presence, parity, smoking status, alcohol consumption, occupational activity, hours of physical exercise, walking, and television viewing.