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. 2021 Nov 15;2021:6671291. doi: 10.1155/2021/6671291

Table 3.

Sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and diagnostic ratio of each clinical feature.

Pooled sensitivity Pooled specificity Pooled LR+ Pooled LR- Pooled DOR
Symptom
Chest tightness 0.31 (0.23, 0.41) 0.92 (0.86, 0.96) 3.8 (1.44, 10.05) 0.71 (0.46, 1.1) 6.73 (1.44, 31.48)
Cough 0.69 (0.66, 0.72) 0.41 (0.39, 0.43) 1.21 (1.06, 1.37) 0.81 (0.7, 0.94) 1.6 (1.2, 2.1)
Diarrhea 0.09 (0.06, 0.11) 0.96 (0.95, 0.97) 2.04 (1.38, 3.04) 0.96 (0.93, 0.99) 2.21 (1.43, 3.42)
Fatigue 0.34 (0.29, 0.39) 0.79 (0.76, 0.81) 1.39 (1.04, 1.87) 0.88 (0.76, 1.03) 1.81 (1.07, 3.06)
Fever 0.78 (0.75, 0.81) 0.35 (0.33, 0.37) 1.09 (1.03, 1.17) 0.72 (0.53, 0.99) 1.62 (1.1, 2.4)
Headache 0.09 (0.07, 0.13) 0.9 (0.88, 0.91) 1.07 (0.78, 1.46) 1.01 (0.99, 1.03) 1.06 (0.74, 1.53)
Myalgia 0.34 (0.28, 0.41) 0.86 (0.82, 0.88) 2 (0.95, 4.22) 0.86 (0.63, 1.16) 2.37 (0.84, 6.65)
Shortness of breath 0.5 (0.46, 0.54) 0.84 (0.83, 0.86) 3.18 (2.24, 4.51) 0.65 (0.51, 0.82) 7.6 (3.59, 16.07)
Sore throat 0.15 (0.12, 0.19) 0.9 (0.88, 0.91) 1.69 (0.81, 3.55) 0.95 (0.87, 1.05) 1.77 (0.73, 4.31)
Sputum production 0.3 (0.26, 0.34) 0.71 (0.68, 0.73) 1.22 (0.95, 1.57) 0.98 (0.92, 1.06) 1.28 (0.9, 1.84)
Comorbidities
Cardiovascular disease 0.14 (0.12, 0.18) 0.97 (0.96, 0.98) 3.45 (2.19, 5.44) 0.87 (0.82, 0.95) 4.18 (2.44, 7.16)
Chronic liver disease 0.04 (0.02, 0.06) 0.96 (0.96, 0.97) 1.36 (0.82, 2.26) 1 (0.98, 1.02) 1.37 (0.8, 2.36)
Chronic renal disease 0.04 (0.02, 0.06) 1 (0.99, 1) 4.79 (2.04, 11.25) 0.98 (0.95, 1) 4.98 (2.08, 11.91)
Chronic respiratory system diseases 0.05 (0.03, 0.08) 0.99 (0.99, 1) 6.07 (3.12, 11.82) 0.97 (0.95, 0.99) 6.53 (3.26, 13.06)
Diabetes 0.19 (0.16, 0.22) 0.94 (0.93, 0.95) 2.82 (1.95, 4.1) 0.89 (0.84, 0.95) 3.25 (2.11, 5.03)
Hypertension 0.34 (0.3, 0.38) 0.87 (0.85, 0.88) 2.53 (1.89, 3.4) 0.78 (0.61, 0.88) 3.47 (2.3, 5.21)
Malignancy 0.05 (0.03, 0.09) 0.98 (0.97, 0.99) 2.83 (1.34, 5.98) 0.98 (0.95, 1) 3.03 (1.38, 6.65)