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. 2021 Nov 8;14:7843–7853. doi: 10.2147/IJGM.S337488

Table 3.

Univariate and Multivariate Analysis for the Diagnosis of COVID-19 Patients

Univariate Analysis Multivariate Analysis
Odds Ratio (OR) 95% C.I. P value Odds Ratio (OR) 95% C.I. P value
Lower Upper Lower Upper
Age (>40) 3.397 1.454 7.937 0.005 5.697 0.487 66.653 0.166
Hb (>12.6) g/dl 0.532 0.243 1.167 0.115
RBCs (>4.6) 106/ul 2.049 0.713 5.890 0.183
HCT (>38.5) % 3.410 1.030 11.296 0.045 30.73 0.760 1243.09 0.070
MCV (<82.4) fL 1.732 0.683 4.394 0.247
MCH (>27) Pg 2.847 0.999 8.114 0.050 3.228 0.216 48.202 0.395
RDW (>13.6) % 0.500 0.115 2.175 0.355
Platelets (>227) ×109/L 0.290 0.127 0.661 0.003 0.045 0.001 1.505 0.083
TLC (>6.5)×109/L 1.065 0.497 2.283 0.872
Neutrophil (>2.9) 103/ul 0.453 0.198 1.034 0.060
Segmented% (>60) 2.000 0.649 6.166 0.228
Eosinophil (>0.05) 103/ul 0.178 0.056 0.560 0.003 0.030 0.001 1.629 0.085
Basophil (>0) 103/ul 1.646 0.683 3.968 0.267
Lymphocytes (>1.5) 103/ul 0.075 0.021 0.264 P<0.001 0.312 0.007 13.647 0.546
CRP (>13.1) mg/L 11.908 3.291 43.090 P<0.001 8.543 0.207 352.901 0.259
Ferritin (>200) ng/L 7.619 0.872 66.541 0.066
D-dimer (>0.33)ng/mL 12.000 3.140 45.855 P<0.001 3.721 0.049 283.207 0.552
NLR (>2.5) 5.412 2.130 13.755 P<0.001 0.158 0.009 2.932 0.216
LMR (<6) 3.828 1.694 8.648 0.001 0.360 0.097 1.335 0.127
PLR (>118) 2.412 1.102 5.280 0.028 0.659 0.191 2.272 0.509
dNLR (>1.7) 1.509 0.703 3.237 0.291
SII (>807) 7.710 2.174 27.340 0.002 3.897 0.269 56.428 0.318
NLPR (>0.011) 21.729 4.885 96.651 P<0.001 38.751 2.080 722.060 0.014
SIRI (>0.8) 4.452 1.738 11.406 0.002 6.68 0.000 0.999
AISI (>252) 3.521 1.371 9.047 0.009 0.884 0.000 0.999
CRP/L (>7.6) 19.000 4.146 87.070 P<0.001 7.604 1.338 43.224 0.022

Note: The P value is significant if <0.05.

Abbreviations: AISI, aggregate index of systemic inflammation; CRP, C-reactive protein; CRP/L, CRP to lymphocyte ratio; dNLR, derived neutrophil to lymphocyte ratio; Hb, haemoglobin concentration; HCT, haematocrit value; LDH, lactate dehydrogenase; MCH, mean corpuscular hemoglobin; MCV, mean corpuscular volume; LMR, lymphocyte to monocyte ratio; NLPR, neutrophil to lymphocyte; platelet ratio; NLR, the neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio; RBCs, red blood cells; RDW, red cell distribution width; SII, systemic inflammation index; SIRI, systemic inflammation response index; TLC, total leukocyte count.