Figure 5.

Cytokine production by innate-like T and T cells in from MR1^−/−mice treated with i6-FP. IFN-γ, TNF-α, and IL-17A intracellular staining of MAIT cells, iNKT cells, γδ T cells, and CD4⁺ and CD8⁺ T cells in splenocytes (A) and LPL (B) from MR1^−/− mice treated with i6-PF (n = 8) or control vehicle (n = 8) 6 hours after phorbol 12-myristate 13-acetate (PMA) and ionomycin stimulation are shown. Data represent the mean ± SEM of each group. Significance was determined using Welch’s t-test. Each symbol represents data from an individual mouse.