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. 2021 Aug 11;13(1):151–171. doi: 10.1016/j.jcmgh.2021.08.002

Figure 3.

Figure 3

Deletion of the Sele gene slightly reduces liver damage in HFD-fed mice. (A–D) WT (n = 7) and Sele KO (n = 6) mice were subjected to 3-month HFD feeding (3M HFD). (E and F) WT (n = 20–23) and Sele KO (n = 23) mice were subjected to 6-month HFD feeding (6M HFD) or chow diet (n = 13) (WT Chow). Sera and liver tissues were collected and analyzed. (A) Serum ALT and AST levels of 3M HFD. (B) H&E staining of liver tissue. (C) Body weight (BW) and liver weight to body weight ratio (LW/BW). (D) MPO immunostaining of liver tissues. (E) Serum ALT and AST levels. (F) BW and LW/BW. (G) Serum glucose levels and (H) GTT and ITT. ∗P < .05.