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. 2021 Sep 24;10:393. Originally published 2021 May 17. [Version 2] doi: 10.12688/f1000research.51785.2

Table 3. Disease progression among anti-hypertensive drugs.

ACEI/ARB: angiotensin-converting enzyme inhibitors and angiotensin receptor blockers; CCB: calcium channel blocker; BB: beta blocker; CI: confidence interval.

Comorbid Mortality
rate(%)
Days of death
(mean)
RR 95%CI
   Geriatri (age>60 years old) 19,35 23,52
   DM 15,79 27,91
   HT 17,95 25,98
   Heart Disease 25,00 22
   Chronic Kidney Disease 0,00 0
AntiHypertensive Drugs
   Single
    ACEI/ARB 7,14 23 0,33 (0,05-2,49)
    CCB 4,55 28,79 0,16 (0,02-1,22)
    BB 54,55 21,11 9,82 (2,33-41,89) *
Double
   ACEI/ARB+CCB 15,38 20,39 0,85 (0,14-5,06)
   ACEI/ARB+BB 14,29 14 0,81 (0,10-6,51)
   CCB+BB 25 15,67 1,27 (0,17-9,72)
Overall
   Single 17,02 25,19 1,28 (0,42-3,49)
   Double 16,67 19,81 1,10 (0,37-3,31)
   Triple 0 0
Severity of Chest X-Ray
   Normal 0 0
   Mild 7,14 19
   Moderate 14,29 18
   Severe and Critcal ill 24,32 25,03
Inflammatory marker
   Leucocyte
    >6.16x10 3/uL 12,99 26,22
    <6,16x10 3/uL 2,60 21,27
Neutrophil-lymphocyte ratio (NLR)
   High (>6.5) 7,79 25,88
   Low (<6,5) 7,79 24
Absolute Lymphocyte Count (ALC)
   Low < 1.0 × 10 3 cells/µL 7,79 23,54
   High > 1.0x10 3 cells/µL 7,79 27,31
CRP
   High (>41,8 mg/L) 6,49 23,26
   Low (<41,8 mg/L) 9,09 27,64
Procalcitonin
   High (>0,07 ng/mL) 9,09 23,96
   Low (<0,07 ng/mL) 6,49 28,07

DM, diabetes mellitus; HT, hypertension; ACE, angiotensin-converting enzyme inhibitors; ARB, angiotensin receptor blockers; BB, beta blocker; CCB, calcium channel blocker; ICU, intensive Care Unit; SD, standard deviation; NLR, Neutrophil-lymphocyte ratio; ALC, Absolute Lymphocyte Count; CRP, C- Reactive Protein; * : marked significantly according 95% confidence interval.