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. 2021 Nov 12;57:231–241. doi: 10.1016/j.jdsr.2021.10.002

Table 1.

Preclinical models mimicking TMD pain conditions shown in this article.

1. Local inflammatory modela 2. Non-local inflammatory model
  • CFA

  • Formalin

  • Mustard oil

  • Carrageenan

  • Capsaicin

  • ATP

  • Cytokines

  • Monosodium iodoacetate

  • Nerve growth factor

  • A

    Oral function model

  • Jaw opening

  • Occlusal interference

  • B

    Jaw muscle pain model

  • Repeated jaw muscle contraction

  • Jaw muscle tendon ligation

  • C

    Psychological stress model

  • Chronic restraint

  • Repeated forced swim

  • Social defeat stress

  • Others

a

Injection of chemicals into the deep craniofacial tissues.