FIG 7.

(A and B) Mortality (A) and weight loss (B) does not significantly differ in mice infected with WT and ΔGRA28 type 1 strain T. gondii parasites. (C) Behavioral changes and fur ruffling phenotypes associated with infection are exacerbated during the acute phase of infection for mice infected with ΔGRA28 parasites compared to that in WT parasites based on a phenotype scoring system. Specifically, mice infected with ΔGRA28 parasites (light gray lines and triangles) exhibited infection-related symptoms at earlier time points than those infected with WT parasites (black lines and circles). Curves beneath lines are the average across all mice at that time point (with lighter gray representing ΔGRA28 knockout parasites and darker gray representing the wild type). *, P < 0.05 after two-way ANOVA and followed by multiple comparisons at each time point.