Table 2.
Univariable and multivariable Cox regression analysis of predictors of chronic kidney disease
| Variables | Univariable Cox analysis | Multivariable Cox analysis | ||
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age (years) | 1.07 (1.06 to 1.08) | <0.001 | 1.06 (1.05 to 1.07) | <0.001 |
| BMI (kg/m2) | 1.04 (1.02 to 1.06) | <0.001 | 1.02 (1.00 to 1.05) | 0.02 |
| Diabetes mellitus | 1.27 (1.08 to 1.49) | <0.01 | 1.63 (1.38 to 1.91) | <0.001 |
| Hypertension | 1.99 (1.57 to 2.53) | <0.001 | 1.40 (1.13 to 1.75) | 0.003 |
| eGFR 60–89 mL/min/1.73 m2 | 5.95 (5.02 to 7.06) | <0.001 | 5.59 (4.70 to 6.65) | <0.001 |
| Female, (%) | 1.33 (1.14 to 1.54) | <0.001 | ||
| Waist (cm) | 1.02 (1.01 to 1.03) | <0.001 | ||
| SBP (mm Hg) | 1.01 (1.00 to 1.01) | <0.001 | ||
| Ever smoking | 0.70 (0.58 to 0.85) | <0.001 | ||
| Ever drinking | 0.83 (0.67 to 1.05) | 0.127 | ||
| Exercise | ||||
| Never | Reference | |||
| Once a week | 0.97 (0.80 to 1.20) | 0.81 | ||
| Few times a week | 1.05 (0.76 to 1.46) | 0.76 | ||
| Daily | 1.17 (0.99 to 1.39) | 0.069 | ||
| RCC (×1012 /L) | 0.61 (0.53 to 0.71) | <0.001 | ||
| Haemoglobin (g/L) | 0.99 (0.98 to 0.99) | <0.001 | ||
| WCC (×109 /L) | 1.05 (1.01 to 1.10) | 0.014 | ||
| PLT (×109 /L) | 1.00 (1.00 to 1.00) | 0.722 | ||
| ALT (U/L) | 1.00 (0.99 to 1.00) | 0.322 | ||
| BUN (mmol/L) | 1.00 (1.00 to 1.01) | 0.855 | ||
| Triglyceride(mmol/L) | 1.12 (1.06 to 1.19) | <0.001 | ||
ALT, alanine aminotransferase; BMI, body mass index; BUN, blood urea nitrogen; eGFR, estimated glomerular filtration rate; PLT, platelet; RCC, red cell count; SBP, systolic blood pressure; WCC, white cell count.