Table 1.
Descriptive characteristics of included studies investigating the impact of polio supplementary immunisation activities (SIAs), 1994–2020
First author, Publication year | WHO region Country/ies |
Setting and population | Main objective | Study design | Study period | Goal of SIA | Author identified study limitations | Funding source and affiliations |
Bawa 201837 | WHO AFRO Nigeria |
Nomadic populations in Northern states of Nigeria | Engagement and immunisation coverage | Cross sectional | 2016 | To boost coverage in nomadic populations | None reported | WHO 42.8% of authors are affiliated with WHO |
Bawa 201932 | WHO AFRO Nigeria |
Hard to access communities in Bauchi, Borno, Kaduna, Kano, Katsina and Yobe | Effectiveness of mobile outreach strategy | Cross sectional cluster survey Pre–post intervention study |
June 2014–September 2015 | To boost coverage in hard to reach communities | Data collection were not uniform across sites | Bill and Melinda Gates Foundation 68.2% of authors are affiliated with WHO and Unicef |
Bedford 201738 | WHO AFRO Liberia |
four counties Montserrado, Nimba, Bong, and Margibi | Barriers and drivers for immunisation | Qualitative focus group | May 2015 | To boost coverage following disruption in polio vaccine coverage during Ebola virus disease outbreaks | Limited timeframe of data collection Potential language issues during focus groups |
No funding declared 57.1% of authors are affiliated with Unicef |
Bonu 200311 | WHO SEARO India |
Rural areas of 4 North Indian states—Bihar, Madhya Pradesh, Rajasthan and Uttar Pradesh | Impact of polio immunisation campaign | Pre–post intervention study Cluster survey |
1992–1999 (intervention in 1995) |
To boost coverage | The Family Health Survey used was not explicitly designed to evaluate the campaign and unable to discern specific campaign components | No funding declared No affiliations with UN agencies |
Bonu, 200412 | WHO AFRO WHO SEARO Sub-Saharan Africa Central Africa: Cameroon Western Africa Burkina Faso Cote d’Ivoire Ghana Kenya Niger Nigeria Southern Africa Malawi Zimbabwe Eastern Africa Rwanda Tanzania Uganda South Asia Bangladesh India Nepal |
3 South Asian and 12 sub-Saharan African countries with comparable pre–post data, mid-to-lower levels of health system performance | Immunisation coverage and equity | Pre–post intervention study Identified cluster survey Study draws on immunisation data of all the 12–23 months old surviving children at the time of the survey. Hence, crude immunisation coverage was estimated, administered ‘by time of survey’, and based on evidence from card/history. |
1990–2001 | To boost coverage | No uniformity in preintervention and postintervention surveys between countries Surveys were conducted at different time points Changes cannot be attributed to specific components of the polio eradication initiative |
No funding declared No affiliations with UN agencies |
Closser, 201439 | WHO AFRO WHO SEARO Ethiopia, Nigeria, Rwanda, Angola, India, Nepal, Pakistan |
eight districts within seven countries in South Asia and sub-Saharan Africa | Relationship between SIA, routine immunisation and primary healthcare | Quantitative component: Cross-national time series analysis Qualitative component: Case studies including document review, semistructured interview and participant observation |
Quantitative: 1990–2010 Qualitative: 2011 |
Scale up of immunisation activities as part of polio eradication initiative activities | The effects observed in the study were highly context specific and cannot be generalised. | Bill & Melinda Gates Foundation No affiliations with UN agencies |
Helleringer, 201640 | WHO SEARO Bangladesh |
National data | Causal effects of SIA on routine immunisation | Quasi-experimental | 2011 | To boost coverage | Sample size too small to estimate effect of SIA on routine immunisation Potential reporting error |
Unicef 33.3% of authors affiliated with Unicef |
Koop, 200141 | WHO EURO North Macedonia |
Albanian Kosovar refugees in Macedonia Refugee camps in Skopje, Tetovo, and Gostivar regions |
Results of extended programme on immunisation | Cross-sectional | May 2011 | To boost coverage particularly among refugee populations | No quality control for data collection | No funding declared No affiliations with UN agencies |
Levin, 200213 | WHO AFRO WHO SEARO Bangladesh Cote d’Ivoire Morocco |
Whole countries | Impact of SIA on financing of routine immunisations | Cross sectional | 1993–1998 | To boost coverage | Non representative countries Did not determine if funding decisions of international agencies were made a t regional or headquarter levels |
United States Agency for International Development No affiliations with UN agencies |
Mangrio, 200867 | WHO EMRO Pakistan |
three rural districts and one town—Nawabshah, Sanghar and Mirpurkhas and Malir Town in Karachi city |
Healthcare worker views, barriers and driers of routine immunisation | Key informant interviews and focus groups | July–September 2005 | To increase routine coverage for polio as part of polio eradication efforts generally | Small scale study | No funding declared No affiliations with UN agencies |
Mello, 201042 | PAHO/WHO Brazil |
27 Brazilian capital cities (including the Federal District) | SIA contribution to routine immunisation coverage | Cross-sectional (household cluster survey) | 2007–2008 | To boost coverage | Not generalisable results for whole country Inconsistent reasons for non-participation |
No funding declared No affiliations with UN agencies |
Nsubuga, 201843 | WHO AFRO 43 of the 47 countries in the African WHO region (quantitative aspect) Cameroon, Democratic Republic of Congo, Nigeria and Uganda (qualitative aspect) |
Entire country | Benefits of polio eradication initiative | Mixed methods | 2017 | Polio eradication campaigns generally | Recall bias | No funding declared No affiliations with UN agencies |
Onyeka, 201444 | WHO AFRO Nigeria |
Anambra state (South Eastern state) | Lessons from SIAs | Cross sectional | Jan-Nov 2010 | To boost coverage | Potential errors in denominator data | No funding declared 25% of authors affiliated with WHO and Unicef |
Poy, 201645 | WHO AFRO Africa |
Case studies of integrated polio SIAs in Cameroon and DR Congo | Impact of polio data management investment on routine immunisation | Descriptive | 2001–2014 | To boost coverage | Some data management support may have come from non-polio funds | No funding declared 100% of authors affiliated with WHO |
Tafesse, 201746 | WHO AFRO Ethiopia |
Somali region | Effects of SIA on routine immunisation | Descriptive | Jun 2013- Jun 2015 | To boost coverage in response to wild-type polio virus outbreak | Data incompleteness | No funding declared 60% of authors affiliated with WHO |
van den Ent, 201747 | WHO AFRO WHO EMRO WHO SEARO Angola, Chad, DRC, Ethiopia, Nigeria, South Sudan, Afghanistan, Pakistan, Somalia, India |
Whole country | Personnel related impact of SIA on routine immunisation | Cross sectional | 2013–2014 | To boost coverage | Self-reported data has potential for bias | Bill and Melinda Gates Foundation 33.3% of authors are affiliated with WHO |
van Turennout, 200368 | WHO AFRO South Africa |
Dikgale-Soekmekaar district (small rural district) | Routine and mass immunisation coverage | Cross sectional Cluster survey |
2000 | To boost coverage | Not generalisable to other South African regions | Vlaamse Inter Universitaire Raad No affiliations with UN agencies |
Verguet, 201369 | WHO AFRO South Africa |
52 South African districts | Impact of SIA on routine child and maternal health services | Interrupted time series | 2001–2010 | To boost coverage | Data quality, non-standardised health records | Bill and Melinda Gates Foundation No affiliations with UN agencies |
Wallace, 201748 | WHO SEARO Nepal |
Central region | Impact of intervention package on routine immunisation | Pre–post intervention | January 2012–September 2013 | To boost coverage | No control group Observed practices may not have been representative |
Centres for Disease Control and Prevention (CDC) 33.3% of authors are affiliated with CDC and 25% of authors are affiliated with WHO |
Zuber, 200370 | WHO AFRO Burkina Faso |
53 health districts | Compare administrative coverage estimates with cluster survey data coverage | Pre–post intervention Cluster survey |
1999 | Assessing accuracy of administrative coverage data collected as part of SIAs | Limited sampling | No funding declared 25% of authors are affiliated with CDC 25% of authors are affiliated with WHO |