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. 2021 Oct 28;23(1):12. doi: 10.3892/etm.2021.10934

Figure 6.

Figure 6

High expression levels of lncRNA H19 and low expression levels of NAT1 predict poor prognosis in patients with breast cancer receiving TAM therapy. Thirty patients were allocated to low and high H19 and NAT1 groups according to whether expression in the tumor tissue was ≥1.5-fold lower or higher than that in the paracancerous tissue. Expression levels of H19 and NAT1 were detected using reverse transcription-quantitative PCR. (A) DFS of patients with TAM therapy in the low and high H19 expression groups. (B) DFS of patients with TAM therapy in the low and high NAT1 expression groups. (C) Pearson correlation analysis was used to measure the association between the expression levels of H19 and NAT1. lncRNA, long non-coding RNA; Cum, cumulative; DFS, disease-free survival; NAT1, N-acetyltransferase 1; TAM, tamoxifen.