Table 3.
Power for detecting differences in rate of adverse pregnancy outcomes (for Aims 3 and 5) based on assumed proportion in the HIV and ZIKV co-infected, HIV- infected and ZIKV-infected groups as compared to the HIV and ZIKV-uninfected group.
|
Percent of enrolled in HIV+/ZIKV+, HIV+/ZIKV-, HIV-/ZIKV+, and HIV-/ZIKV- groups |
Power for detecting 2-fold difference in odds of adverse outcomes for HIV+/ZIKV+, HIV+/ZIKV-, and HIV-/ZIKV+ groups vs. HIV-/ZIKV- group, based on assumed background rates in reference group | ||
|---|---|---|---|
| 5% | 10% | 20% | |
| 12, 28, 12, 48% | 66.4, 85.7, 66.4% | 89.6, 98.5, 89.6% | 98.5, 100, 98.5% |
| 20, 20, 24, 36% | 73.7, 73.7, 77.0% | 94.2, 94.2, 95.8% | 99.6, 99.6, 99.8% |
| 15, 35, 10, 40% | 69.5, 84.9, 58.6% | 91.8, 98.4, 83.6% | 99.1, 100, 96.6% |
| 25, 25, 20, 30% | 72.9, 72.9, 69.3% | 94.0, 94.0, 92.0% | 99.6, 99.6, 99.3% |
| 18, 42, 8, 32% | 68.9, 80.8, 49.5% | 91.6, 97.3, 74.8% | 99.2, 99.9, 92.3% |
| 30, 30, 16, 24% | 68.3, 68.3, 59.6% | 91.8, 91.8, 85.2% | 99.4, 99.4, 97.7% |