Table 5.
Comparison of SCL-90-R score, psychosis phenotype, and clinical diagnosis between Classes (n = 939)
| Class 1 (High Risk) N = 490 (52.2%) |
Class 2 (Depression) N = 337 (35.9%) |
Class 3 (Prototypical Scizophrenia) N = 51 (5.4%) |
Class 4 (Schizophrenia/Depression) N = 61 (6.5%) |
Class 1 β(95%CI) |
Class 2 β(95%CI) |
Class 3 β(95%CI) |
Class 4 β(95%CI) |
Class 4 vs.3 β(95%CI) |
|
|---|---|---|---|---|---|---|---|---|---|
|
Psychotic Experiences (SCL-90-R) |
27.40 ± 4.45 | 29.30 ± 5.45 | 39.67 ± 10.35 | 42.80 ± 10.17 | 0 (ref) |
1.91***$ (1.11–2.72) |
12.26***$ (10.6–13.93) |
15.42***$ (13.88–16.97) |
2.93 (−0.9–6.76) |
| Paranoid ideation subscale | 11.00 ± 2.96 | 11.12 ± 3.39 | 15.18 ± 4.15 | 16.15 ± 4.18 | 0 (ref) |
0.10 (−0.35–0.56) |
4.18***$ (3.23–5.12) |
5.13***$ (4.25–6.00) |
0.85 (− 0.70–2.39) |
| Psychoticism subscale | 16.40 ± 3.56 | 18.18 ± 4.23 | 24.49 ± 6.48 | 26.66 ± 6.70 | 0 (ref) |
1.81***$ (1.22–2.40) |
8.09***$ (6.86–9.32) |
10.29***$ (9.16–11.43) |
2.08 (− 0.39–4.56) |
|
Class 1 OR(95%CI) |
Class 2 OR (95%CI) |
Class 3 OR (95%CI) |
Class 4 OR (95%CI) |
Class 4 vs.3 OR (95%CI) |
|||||
| Hallucinations and Delusions | 115 (23.5%) | 38 (11.3%) | 27 (52.9%) | 34 (55.7%) | 1 (ref) |
0.40***$ (0.27–0.60) |
3.71***$ (2.05–6.72) |
3.93***$ (2.26–6.85) |
1.07 (0.50–2.27) |
| Schizophrenia nuclear symptoms | 131 (26.7%) | 66 (19.6%) | 50 (98.0%) | 55 (90.2%) | 1 (ref) |
0.65* (0.47–0.92) |
144.17***$ (19.68–1056.25) |
26.35***$ (11.03–62.96) |
0.21 (0.02–1.84) |
| Nuclear symptoms and Depression | 0 (0%) | 37 (11%) | 0 (0%) | 45 (73.8%) | 1 (ref) | n.a. | n.a. | n.a. | n.a. |
| Depression (cutoff) | 0 (0%) | 195 (57.9%) | 0 (0%) | 51 (83.6%) | 1 (ref) | n.a. | n.a. | n.a. | n.a. |
| Diagnosed Schizophrenia | 4 (0.8) | 7 (2.1) | 1 (2.0) | 2 (3.3) | 1 (ref) | 2.57 (0.74–8.92) | 2.14 (0.23–19.97) |
3.13 (0.53–18.53 |
1.38 (0.11–17.44) |
| Diagnosed Non-Psychotic Disorder | 90 (18.4) | 99 (29.4) | 11 (21.6) | 20 (32.8) | 1 (ref) |
1.84***$ (1.33–2.56) |
1.21 (0.60–2.45) |
2.09* (1.17–3.75) |
1.72 (0.71–4.16) |
Adjusted for age and sex
$: significance after correction for regressions of 21 variables using Bonferroni’s correction and the new threshold is 0.05/21 = 0.0024