Table 2.
Analyzes of genes from The Cancer Genome Atlas (TCGA) samples from 103 Skin Cutaneous Melanoma (SKCM) patients
| Up-regulated genes in alive × dead | ||
|---|---|---|
| Gene.symbol | log2FC | FDR |
| SLC5A4 | 4.35910 | 1.29E−09 |
| VGF | 3.26059 | 1.06E−05 |
| NPPC | 3.24826 | 2.60E−05 |
| LINC00698 | 3.76414 | 3.90E−05 |
| SPACA3 | 2.67598 | 1.97E−04 |
| VCX3A | 4.95714 | 2.21E−04 |
| PRSS56 | 4.13411 | 4.15E−04 |
| ARHGAP8 | 2.75929 | 4.15E−04 |
| VCX | 3.63292 | 4.28E−04 |
| LINC01287 | 3.48781 | 7.19E−04 |
| NGFR | 1.99998 | 1.16E−03 |
| NAT16 | 2.23940 | 1.16E−03 |
| RP13-143G15.4 | 2.26728 | 1.34E−03 |
| HLA-J | 1.67323 | 1.38E−03 |
| LHFPL4 | 2.80159 | 2.04E−03 |
| RP11-376N17.4 | 2.27953 | 2.10E−03 |
| ZNF689 | 1.08305 | 2.33E−03 |
| DCD | 6.91950 | 2.44E−03 |
| SLITRK5 | 2.38821 | 2.59E−03 |
| ARPP21 | 3.84108 | 2.67E−03 |
| TFAP2B | 2.73943 | 2.68E−03 |
| VIT | 2.42509 | 3.21E−03 |
| HPCAL4 | 1.70772 | 3.30E−03 |
| LINC00645 | 3.54408 | 4.05E−03 |
| KLHL32 | 1.29974 | 4.09E−03 |
| TRIML2 | 2.32595 | 4.80E−03 |
| GFAP | 2.04141 | 5.21E−03 |
| MYOZ2 | 2.33172 | 6.94E−03 |
| PPY | 2.13167 | 7.88E−03 |
| ARX | 2.02055 | 8.39E−03 |
| LRRTM2 | 1.75474 | 8.39E−03 |
| C20orf203 | 1.95612 | 8.43E−03 |
| LSMEM2 | 1.36377 | 8.43E−03 |
| NRTN | 1.74226 | 8.58E−03 |
| RP11-809C18.3 | 1.54681 | 8.89E−03 |
| FOSB | 1.08702 | 9.10E−03 |
| PASD1 | 4.57206 | 9.14E−03 |
| UNC93B3 | 1.84987 | 9.14E−03 |
| RP11-469H8.6 | 2.35144 | 9.14E−03 |
| BCO1 | 2.17260 | 9.80E−03 |
| XKR7 | 1.93913 | 1.00E−02 |
| RDH5 | 1.36688 | 1.04E−02 |
| PAGE1 | 3.69526 | 1.10E−02 |
| RP5-907D15.4 | 1.73346 | 1.10E−02 |
| AC003092.1 | 2.31155 | 1.20E−02 |
| IGHV1-58 | 3.09550 | 1.20E−02 |
| FOXG1 | 3.56195 | 1.36E−02 |
| GBA3 | 2.67229 | 1.39E−02 |
| FKSG51 | 1.89383 | 1.39E−02 |
| BTNL8 | 1.87248 | 1.46E−02 |
| ACHE | 1.18749 | 1.52E−02 |
| KCNJ11 | 1.81031 | 1.52E−02 |
| ENPP7P2 | 1.45231 | 1.64E−02 |
| CCKBR | 2.06353 | 1.73E−02 |
| PCSK1N | 1.87835 | 1.76E−02 |
| RP11-114G11.5 | 3.04186 | 1.76E−02 |
| EFTUD1P1 | 2.13819 | 1.77E−02 |
| OR2N1P | 5.08848 | 1.83E−02 |
| CA10 | 2.21148 | 1.85E−02 |
| SLCO5A1 | 1.55420 | 1.88E−02 |
| IBSP | 1.81676 | 1.91E−02 |
| RP11-88I21.1 | 3.56590 | 1.94E−02 |
| MAGEA9 | 5.10603 | 1.96E−02 |
| SYP | 1.03514 | 2.15E−02 |
| NBEAP1 | 1.55393 | 2.17E−02 |
| RP5-965G21.4 | 1.14894 | 2.18E−02 |
| MPZ | 1.95997 | 2.22E−02 |
| RP11-299H22.3 | 2.95030 | 2.22E−02 |
| FBXO2 | 1.34819 | 2.31E−02 |
| LGSN | 2.41190 | 2.31E−02 |
| RDH8 | 2.14341 | 2.32E−02 |
| AC073325.2 | 1.90901 | 2.38E−02 |
| GAGE1 | 3.92238 | 2.44E−02 |
| MYB | 1.16344 | 2.55E−02 |
| AATK | 1.23997 | 2.63E−02 |
| DOK7 | 1.48390 | 2.72E−02 |
| AC068580.7 | 2.45353 | 2.72E−02 |
| RP11-36D19.9 | 1.99056 | 2.72E−02 |
| HAPLN2 | 1.51979 | 2.73E−02 |
| TDRD12 | 2.24362 | 3.09E−02 |
| RP11-159H10.3 | 1.83751 | 3.18E−02 |
| CHGB | 1.62908 | 3.32E−02 |
| RCN3 | 1.25033 | 3.32E−02 |
| RP5-1171I10.5 | 1.33948 | 3.32E−02 |
| NMRK2 | 2.15724 | 3.33E−02 |
| TNNI3 | 1.50305 | 3.33E−02 |
| DPEP3 | 1.81124 | 3.33E−02 |
| DPYSL5 | 2.12990 | 3.33E−02 |
| ZNF365 | 1.53513 | 3.39E−02 |
| KCNQ2 | 1.98246 | 3.51E−02 |
| PMP2 | 2.27248 | 3.53E−02 |
| HAVCR1 | 2.17185 | 3.56E−02 |
| RP1-140K8.5 | 1.72113 | 3.72E−02 |
| ROR1-AS1 | 2.03339 | 3.75E−02 |
| C1QTNF1-AS1 | 1.82857 | 3.75E−02 |
| WFDC1 | 1.74139 | 3.99E−02 |
| DEFB126 | 2.40171 | 3.99E−02 |
| LBP | 1.71514 | 3.99E−02 |
| CDH12 | 2.39970 | 3.99E−02 |
| FABP7 | 2.11963 | 3.99E−02 |
| MAGEB17 | 1.73309 | 3.99E−02 |
| MYBPC1 | 1.99301 | 3.99E−02 |
| RP4-764D2.1 | 1.03824 | 4.07E−02 |
| CD5L | 1.77129 | 4.21E−02 |
| CPN2 | 1.81842 | 4.21E−02 |
| ZNF727 | 2.20430 | 4.21E−02 |
| CST1 | 2.16587 | 4.35E−02 |
| RP11-9G1.3 | 2.55148 | 4.48E−02 |
| LL22NC03-22D1.1 | 2.49624 | 4.50E−02 |
| NPFFR1 | 1.60868 | 4.54E−02 |
| MYRIP | 1.45769 | 4.67E−02 |
| RP11-369C8.1 | 2.61906 | 4.95E−02 |
| Down-regulated genes in alive × dead | ||
|---|---|---|
| Gene.symbol | log2FC | FDR |
| AVPR1A | − 2.06066 | 8.65E−08 |
| KRT16P2 | − 5.08308 | 1.00E−07 |
| CHST8 | − 3.38063 | 7.38E−07 |
| ST6GAL2 | − 2.68516 | 1.74E−06 |
| PRSS35 | − 3.35395 | 4.71E−6 |
| SLC8A3 | − 3.18840 | 9.15E−06 |
| CRABP1 | − 3.07142 | 9.15E−6 |
| HSPB3 | − 3.24770 | 2.15E−05 |
| TREX2 | − 2.43750 | 2.15E−05 |
| B3GNT4 | − 1.77784 | 2.26E−05 |
| NPTX1 | − 2.61603 | 1.97E−04 |
| PI3 | − 3.60121 | 2.70E−04 |
| HEYL | -1.67534 | 2.99E−04 |
| ID3 | − 1.32736 | 3.67E−04 |
| ADRB2 | − 1.81924 | 3.91E−04 |
| C6orf223 | − 2.13191 | 4.15E−04 |
| AJAP1 | − 1.92423 | 4.56E−04 |
| CHRNA4 | − 2.95110 | 4.69E−04 |
| RHCG | − 2.92093 | 5.10E−04 |
| PART1 | − 2.14901 | 5.50E−04 |
| ALOX12 | − 1.23574 | 5.50E−04 |
| RSPO3 | − 1.48997 | 6.13E−04 |
| GDPD3 | − 1.74062 | 7.38E−04 |
| CNFN | − 2.84236 | 8.27E−04 |
| ANO2 | − 1.70534 | 9.14E−04 |
| OVOL1 | − 2.75293 | 9.14E−04 |
| CLDN4 | − 2.52180 | 9.56E−04 |
| GREB1L | − 2.35313 | 1.12E−03 |
| IGLV9-49 | − 3.84182 | 1.20E−03 |
| TGM1 | − 2.85878 | 1.28E−03 |
| CYSRT1 | − 2.10472 | 1.34E−03 |
| LYPD5 | − 2.27815 | 1.34E−03 |
| CYP19A1 | − 1.84923 | 1.41E−03 |
| ACTG2 | − 1.63424 | 1.41E−03 |
| ABCG4 | − 2.12582 | 1.41E−03 |
| FAM3D | − 2.12972 | 1.41E−03 |
| PAPSS2 | − 1.50601 | 1.41E−03 |
| AC124789.1 | − 2.07689 | 1.41E−03 |
| RASL11B | − 1.54784 | 1.43E−03 |
| MAFB | − 1.28214 | 1.43E−03 |
| NGF | − 1.73693 | 2.01E−03 |
| AC006116.20 | − 1.47472 | 2.01E−03 |
| S100A12 | − 2.64402 | 2.10E−03 |
| KLK14 | − 2.29647 | 2.39E−03 |
| IL1RN | − 2.09008 | 2.39E−03 |
| B3GNT8 | − 1.78028 | 2.39E−03 |
| GPX3 | − 1.88978 | 2.39E−03 |
| CDA | − 2.22423 | 2.68E−03 |
| CHN1 | − 1.30585 | 2.68E−03 |
| PRSS27 | − 1.71351 | 2.68E−03 |
| TMEM79 | − 1.43989 | 3.52E−03 |
| NOTCH3 | − 1.22297 | 3.57E−03 |
| FGF18 | − 1.35348 | 3.80E−03 |
| HGF | − 1.19158 | 4.28E−03 |
| SH3RF3 | − 1.23159 | 4.49E−03 |
| KRT37 | − 4.22818 | 4.57E−03 |
| SH3RF3-AS1 | − 1.31293 | 4.57E−03 |
| ZC3H12A | − 1.35742 | 4.67E−03 |
| TBX4 | − 1.84817 | 5.39E−03 |
| CLIC3 | − 2.31078 | 5.58E−03 |
| LRRC43 | − 1.34142 | 5.69E−03 |
| NRARP | − 1.42862 | 5.97E−03 |
| B3GNT3 | − 1.97566 | 6.61E−03 |
| ELF3 | − 2.07351 | 6.73E−03 |
| LRRN2 | − 1.90993 | 6.80E−03 |
| NFE4 | − 2.76901 | 6.80E−03 |
| KLK10 | − 2.72909 | 6.94E−03 |
| LINC01121 | − 1.68460 | 7.15E−03 |
| SDCBP2 | − 1.48707 | 7.88E−03 |
| FAM83G | − 1.50253 | 7.88E−03 |
| ZNF469 | − 1.06394 | 7.88E−03 |
| ROR2 | − 1.15831 | 7.92E−03 |
| LYNX1 | − 1.75074 | 7.92E−03 |
| VSIG10L | − 1.54237 | 7.92E−03 |
| PITX1 | − 2.50531 | 8.39E−03 |
| PNMA5 | − 2.07397 | 8.43E−03 |
| LTB4R2 | − 1.38009 | 8.43E−03 |
| GTSF1 | − 1.95376 | 8.89E−03 |
| RP3-449H6.1 | − 2.80745 | 8.89E−03 |
| PKDCC | − 1.47224 | 9.03E−03 |
| C11orf87 | − 1.86276 | 9.10E−03 |
| C9orf47 | − 1.63063 | 9.10E−03 |
| KLK12 | − 3.43996 | 9.10E−03 |
| SPNS2 | − 1.33949 | 9.43E−03 |
| TCHH | − 1.56077 | 1.00E−02 |
| ADRA1D | − 1.45232 | 1.01E−02 |
| LINC00675 | − 2.28274 | 1.01E−02 |
| GLP1R | − 1.93142 | 1.04E−02 |
| DLX5 | − 1.61403 | 1.05E−02 |
| JUP | − 1.81687 | 1.10E−02 |
| GREM1 | − 1.36182 | 1.10E−02 |
| FUT2 | − 1.65558 | 1.10E−02 |
| FLJ43879 | − 1.73000 | 1.10E−02 |
| RP4-530I15.9 | − 1.37950 | 1.10E−02 |
| ADAMTSL4 | − 1.15965 | 1.10E−02 |
| LGALS9C | − 1.74166 | 1.11E−02 |
| RP11-145A3.1 | − 1.28593 | 1.20E−02 |
| LINC00689 | − 2.44100 | 1.20E−02 |
| RP11-57C13.6 | − 2.13756 | 1.20E−02 |
| WNT11 | − 1.67218 | 1.23E−02 |
| SOX11 | − 1.31510 | 1.27E−02 |
| SMCO2 | − 1.86262 | 1.29E−02 |
| AC104654.2 | − 1.54674 | 1.34E−02 |
| RP11-715H19.2 | − 2.54830 | 1.45E−02 |
| MALL | − 1.65870 | 1.50E−02 |
| SLPI | − 2.56276 | 1.50E−02 |
| ZNF385B | − 1.82165 | 1.52E−02 |
| AC079305.10 | − 1.07337 | 1.52E−02 |
| RARRES1 | − 1.09119 | 1.56E−02 |
| C1orf177 | − 1.80915 | 1.64E−02 |
| MIR4635 | − 1.81095 | 1.68E−02 |
| KCNK12 | − 1.74033 | 1.70E−02 |
| CTC-525D6.2 | − 3.65998 | 1.75E−02 |
| FGF7 | − 1.14265 | 1.76E−02 |
| KRT82 | − 2.71344 | 1.76E−02 |
| CTD-2554C21.3 | − 2.09957 | 1.76E−02 |
| VNN3 | − 1.87348 | 1.94E−02 |
| KRT17P6 | − 2.54509 | 1.94E−02 |
| CD36 | − 1.47332 | 1.98E−02 |
| ALDH1L1 | − 1.84277 | 1.99E−02 |
| KRT25 | − 3.64328 | 2.04E−02 |
| GLIS3 | − 1.24797 | 2.06E−02 |
| SPRR2D | − 2.65861 | 2.06E−02 |
| CEACAM19 | − 1.48405 | 2.11E−02 |
| ZNF154 | − 1.19730 | 2.12E−02 |
| FBLIM1 | − 1.00682 | 2.15E−02 |
| OR7E11P | − 3.14060 | 2.15E−02 |
| ZNF185 | − 1.43741 | 2.27E−02 |
| MYOC | − 3.14651 | 2.30E−02 |
| SULT2B1 | − 2.16618 | 2.31E−02 |
| PLA2G4E−AS1 | − 1.49669 | 2.32E−02 |
| IL36G | − 2.54342 | 2.39E−02 |
| IGKV2-29 | − 3.58127 | 2.43E−02 |
| PADI3 | − 1.60173 | 2.45E−02 |
| WDR87 | − 2.67496 | 2.45E−02 |
| CTD-2555C10.3 | − 1.62741 | 2.45E−02 |
| SMPD3 | − 1.51129 | 2.63E−02 |
| LYPD3 | − 2.15151 | 2.63E−02 |
| SPINK9 | − 2.18753 | 2.63E−02 |
| RP3-405J10.2 | − 1.89008 | 2.63E−02 |
| KRT17 | − 2.51044 | 2.65E−02 |
| RP11-845M18.6 | − 2.34005 | 2.70E−02 |
| CPXM2 | − 1.33321 | 2.72E−02 |
| GDPD2 | − 1.69177 | 2.79E−02 |
| LINC01482 | − 1.58713 | 2.84E−02 |
| KRT8P13 | − 2.24864 | 3.07E−02 |
| ANGPT2 | − 1.42767 | 3.23E−02 |
| TMEM45B | − 1.81149 | 3.23E−02 |
| KLK13 | -2.41601 | 3.23E−02 |
| IGHE | − 2.55145 | 3.23E−02 |
| SPRR2A | − 2.94281 | 3.23E−02 |
| RP11-91J3.3 | − 1.87453 | 3.23E−02 |
| CTC-490G23.2 | − 2.34066 | 3.32E−02 |
| ADAMTS15 | − 1.20759 | 3.33E−02 |
| RHOD | − 1.51767 | 3.33E−02 |
| COL28A1 | − 1.56903 | 3.33E−02 |
| RP11-752L20.3 | − 1.07531 | 3.33E−02 |
| AC133785.1 | − 2.02852 | 3.47E−02 |
| GNA15 | − 1.37100 | 3.49E−02 |
| FAM46B | − 1.22702 | 3.53E−02 |
| KRT80 | − 2.07094 | 3.53E−02 |
| TWIST2 | − 1.11079 | 3.53E−02 |
| KRT42P | − 2.45179 | 3.53E−2 |
| PRSS50 | − 1.86776 | 3.64E−02 |
| TBX1 | − 1.26122 | 3.69E−2 |
| KRT81 | − 1.69382 | 3.75E−02 |
| ALOX12B | − 2.41352 | 3.75E−02 |
| KCNMA1-AS1 | − 1.82562 | 3.79E−02 |
| HS3ST3A1 | − 1.28721 | 3.84E−02 |
| USP2 | − 1.07928 | 3.99E−02 |
| BMP4 | − 1.23615 | 3.99E−02 |
| G6PC2 | − 2.36196 | 3.99E−02 |
| RP11-169K16.4 | − 1.98903 | 3.99E−02 |
| COL8A1 | − 1.22669 | 4.09E−02 |
| SIX2 | − 1.02697 | 4.09E−02 |
| KRT17P2 | − 2.21877 | 4.21E−02 |
| BDKRB1 | − 1.22248 | 4.35E−02 |
| LINC00857 | − 1.30729 | 4.35E−02 |
| CREB3L1 | − 1.04632 | 4.44E−02 |
| CCBE1 | − 1.04094 | 4.44E−02 |
| PRR15L | − 1.31182 | 4.48E−02 |
| ST8SIA2 | − 1.70296 | 4.50E−02 |
| S100A9 | − 2.02615 | 4.55E−02 |
| SIK1 | − 1.83293 | 4.60E−02 |
| EPN3 | − 1.93269 | 4.65E−02 |
| ZBTB16 | − 1.22227 | 4.67E−02 |
| ATP8B5P | − 1.00252 | 4.76E−02 |
| DUOX1 | − 1.72011 | 4.78E−02 |
| TRIM53CP | − 2.79481 | 4.80E−02 |
| C6orf132 | − 1.81165 | 4.87E−02 |
| MDFI | − 1.36942 | 4.91E−02 |
| CATSPERB | − 1.85527 | 4.94E−02 |
| HSPE1P5 | − 1.47888 | 4.94E−02 |
| DEFB4A | − 3.10613 | 4.95E−02 |
| SDC1 | − 1.36628 | 4.96E−02 |