Table 3.
Rhesus macaque, cynomolgus macaque, African green monkey and ferret study information.
| Day 1 | Day 7 | Day 14 | |||||
|---|---|---|---|---|---|---|---|
| Animal model | Symptoms | No. studies | No. animals | No. studies | No. animals | No. studies | No. animals |
| Rhesus macaque | Fever | 7 | 41 | 8 | 34 | 5 | 254 |
| Malaise | 7 | 41 | 5 | 22 | 4 | 17 | |
| Pneumonia | 7 | 40 | 6 | 26 | 6 | 26 | |
| Lymphopenia | 7 | 30 | — | — | — | — | |
| Leukocytosis | 6 | 29 | — | — | — | — | |
| High ALT | 5 | 23 | 2 | 10 | 2 | 10 | |
| High AST | 2 | 10 | 2 | 10 | 2 | 10 | |
| Low Albumin | 2 | 10 | 2 | 6 | 2 | 6 | |
| High BUN | — | — | 2 | 6 | — | — | |
| High creatinine | 2 | 10 | 2 | 6 | — | — | |
| Cynomolgus macaque | Fever | 4 | 16 | 4 | 16 | 3 | 13 |
| Malaise | 3 | 20 | — | — | — | — | |
| African green monkey | Fever | 2 | 12 | — | — | — | — |
| Malaise | 3 | 20 | 2 | 10 | — | — | |
| Ferret | Fever | 3 | 18 | 2 | 6 | 2 | 4 |